PROSTATE CANCER (DIAGNOSIS)

This study tests whether a daily pill (abiraterone with prednisone) can lower testosterone enough to control prostate cancer, avoiding the usual hormone-blocking injections. About 60 men with high-risk or advanced prostate cancer will take the pill for 30 days to see if it works.…

This early-stage study tests two types of targeted radiation therapy (177Lu-PSMA-617 and 225Ac-PSMA-617) in 45 men with high-risk prostate cancer who are scheduled for prostate removal surgery. The goal is to see which therapy delivers more radiation to the tumor and how it affec…

This study is testing a new blood test that looks at proteins in platelets (a type of blood cell) to see if it can find prostate cancer more accurately than current methods like PSA tests and biopsies. Researchers at Duke University will enroll 300 men who are already being check…

This study is testing whether new types of MRI scans can more accurately find and grade prostate cancer without using contrast dye. About 300 men with suspected prostate cancer will get both standard and new MRI scans. The results will be checked against biopsy or surgery results…

This study tests a new robot called ProBot that helps doctors perform prostate biopsies with greater precision and less discomfort. The robot uses a special ultrasound probe and can be used for both standard and targeted biopsies. The trial will enroll 60 men aged 40 to 75 who ar…

This study aims to develop a blood test that uses genetic material from tiny particles (exosomes) to predict whether prostate cancer has spread to the bones. Researchers will analyze blood samples from 1,000 men with newly diagnosed prostate cancer and compare the results to PSMA…

This study aims to see if a new type of PET/CT scan, called ACP3, can find prostate cancer tumors as well as or better than current standard scans. About 100 adults with newly diagnosed or recurrent prostate cancer will receive both types of scans. Researchers will compare how ma…

This study compares two prostate biopsy techniques to find which better detects aggressive prostate cancers while avoiding overdiagnosis of harmless ones. About 592 men with a suspicious MRI finding will be randomly assigned to one of two biopsy methods. The goal is to improve ac…

This study tests whether combining PSMA PET scans with machine learning can accurately determine how aggressive a prostate cancer is without needing invasive biopsies. Researchers will scan 220 men with suspected or known prostate cancer and use AI to predict the cancer's Gleason…

This study tests a new way to decide who needs a prostate biopsy. Instead of relying only on MRI, it adds a blood test called Prostate Health Index (PHI) to better tell which men have dangerous prostate cancer. The goal is to safely skip biopsies in men who don't need them, reduc…

This study tests a 12-week prehabilitation program for 20 prostate cancer patients about to start hormone therapy and radiation. The program includes exercise training and a 4-day residential workshop with education and activities. The goal is to see if patients and their familie…

This study tests whether a digital exercise program with virtual group sessions helps prostate cancer patients on hormone therapy stick to exercise guidelines. Hormone therapy can cause fatigue, weight gain, and muscle loss, but exercise can help. The trial will enroll 160 men an…

This study follows 500 men who had their prostate removed for cancer. Researchers check PSA levels soon after surgery to see if they can predict if the cancer will come back or spread. No new treatments are given—just standard care and monitoring.

This study follows 100 men who had a prostate MRI showing suspicious spots but no significant cancer on their first biopsy. Researchers will repeat MRIs and biopsies over time to see if changes in those spots can predict future cancer. The goal is to learn which men need closer m…

This study looks at how well a virtual oncology program works for veterans newly diagnosed with lung, colorectal, prostate, or breast cancer. Researchers will track telehealth visits, quality of care, and costs over 36 months. The goal is to see if this program helps veterans get…

This study looks at whether adding a PSMA PET scan to the usual MRI scan can better find prostate cancer that has come back after focal therapy (a treatment that targets only the tumor). About 62 men who have had focal therapy will get both scans. The goal is to see if the PSMA P…

This study is for men with prostate cancer who are getting a type of radiation called brachytherapy. Researchers want to see how the immune system changes during treatment. They will take blood and tissue samples before, during, and after the procedure. The goal is to learn more,…

This study aims to describe the characteristics of prostate cancer in Algeria, including patient demographics, symptoms, diagnosis methods, and treatments. Researchers will collect information from 2,000 patients aged 19 and older with confirmed prostate cancer. The goal is to be…