AI and PET scans could replace needle biopsies for prostate cancer grading
NCT ID NCT07266129
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining PSMA PET scans with machine learning can accurately grade prostate cancer without invasive biopsies. Researchers will enroll 220 men with suspected or confirmed prostate cancer. If successful, this approach could reduce unnecessary biopsies and help doctors better identify aggressive tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 220 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Primary prostate cancer patients.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * For patients who have undergone biopsies prior to PET: * Patients referred to clinical PET examination * For patients who have not had biopsies prior to PET: * Patients referred to urologist for suspected prostate cancer based on clinical symptoms or elevated PSA-levels Exclusion Criteria: * Prostatektomy * Body weight under 100 kg * MRI incompatible implants or other incompatibilities
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universitetssykehuset Nord Norge, Tromsø
RECRUITINGTromsø, Troms, 9019, Norway
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New MRI techniques could spare men from unnecessary prostate biopsies
- A sharper eye on prostate cancer return: PSMA PET vs. MRI
- AI may help spot dangerous prostate cancer and spare men from needless biopsies
- Blood test may spot prostate cancer without a needle
- AI reads scans to spot prostate cancer, spare unnecessary biopsies
- Extra numbing shot may ease pain of prostate biopsy