PREGNANCY COMPLICATIONS

This study tests whether adding a specially trained doula to standard care helps new moms with pregnancy-related high blood pressure get healthier after birth. About 454 women will either get usual blood pressure monitoring or extra support including a doula, weight checks, and b…

This study compares an automated insulin delivery system (CamAPS FX) to standard insulin therapy in 305 women with type 1 diabetes who are planning pregnancy or are in early pregnancy. The goal is to see if the automated system helps keep blood sugar in a healthy range and improv…

This study tests whether adding certolizumab to standard treatment (heparin and low-dose aspirin) can prevent pregnancy complications like fetal death or early delivery in pregnant women with antiphospholipid syndrome (APS) and lupus anticoagulant. About 55 women will receive the…

This study tests a new method called U-CaVIT, which uses a balloon catheter to prevent severe bleeding after cesarean delivery in women at high risk. About 70 participants will receive either standard care or standard care plus the balloon. The goal is to see if the balloon reduc…

This study tests whether providing money specifically for healthy foods during pregnancy can prevent excessive weight gain and related problems like high blood pressure and diabetes. About 1,440 pregnant women will either receive standard care or extra funds (up to $3,000) to buy…

This pilot study tests a gentle strength and resistance exercise program designed for high-risk pregnant women who are on bed rest in the hospital. The goal is to see if these simple bed-based exercises can improve physical health, emotional well-being, sleep, and quality of life…

This study looks at how the natural bacteria (microbiome) and chemical profiles (metabolome) in couples undergoing IVF might affect their chances of getting pregnant and having a baby. Researchers will collect samples from both partners and track outcomes like fertilization, misc…

This study will use ultrasound to track changes in muscle, fat, and fluid levels in critically ill pregnant and gynecological patients. Researchers want to see if these body changes are linked to serious outcomes like death, need for a breathing machine, or longer ICU stays. Abou…

This study tests a decision support tool called Periviable GOALS for parents facing the threat of an extremely early delivery (between 22 and 25 weeks of pregnancy). The tool provides clear information about outcomes and helps parents clarify their values. About 216 pregnant adul…

This study looks back at the pregnancy history of 50 women who were later diagnosed with lupus. The goal is to find out how often pregnancy complications like miscarriage or pre-eclampsia happen before lupus is detected. By understanding these early signs, doctors may be able to …

This study is testing two new ultrasound methods to see if they can tell the difference between healthy pregnancies and those affected by fetal growth restriction (FGR), where the baby is smaller than expected. Researchers will compare these new scans in 60 pregnant women, some w…