POSTOPERATIVE DELIRIUM

This study looks at whether giving a common painkiller (paracetamol) through an IV can lower the chance of confusion or delirium after surgery in older adults (age 60+). About 1,092 participants who have moderate to severe pain after non-cardiac surgery will receive either parace…

This study looks at whether a drug called remimazolam can lower the chance of confusion (delirium) in older adults after stomach cancer surgery. About 170 people aged 65 and older will get either remimazolam or standard anesthesia. The main goal is to see who has less confusion i…

This study tests three different doses of esketamine (a drug related to ketamine) to see if it can reduce confusion, memory problems, and other brain-related side effects in older adults after major non-cardiac surgery. About 120 patients aged 65 to 90 will receive esketamine dur…

This study looks at whether giving ibuprofen during and after lung surgery can help maintain healthy oxygen levels in the brain and lower the risk of confusion or memory problems afterward. About 54 adults having keyhole lung surgery will be randomly assigned to receive ibuprofen…

This study looks at whether measuring sugar use in a key brain area (the hippocampus) before surgery can help predict which older adults with type 2 diabetes are more likely to become confused or delirious after an operation. Researchers will enroll 154 patients aged 65 and older…

This study looks at whether the way you sleep before heart surgery is connected to problems like confusion (delirium) or kidney injury after the operation. Researchers will track 549 adults having planned heart surgery with a heart-lung machine. The goal is to find patterns that …

This study watches 400 older adults (65+) having planned hip replacement surgery in the Czech Republic. Researchers want to see if a short memory test given before surgery can predict who will become confused or delirious afterward. No new drugs or procedures are tested—just care…

This study looks at whether a blood sugar measurement taken before surgery can help predict if a patient will become confused or delirious afterward. Researchers will review records from 15,000 adults who had non-brain, non-heart surgeries. No new treatments are being tested—the …

This study looks at whether measuring the optic nerve sheath (the protective layer around the nerve at the back of the eye) using ultrasound can help predict delirium—sudden confusion or agitation—after heart surgery. Delirium is common in older adults after surgery and can slow …

This study will test a simple score to predict which patients may develop confusion (delirium) after planned heart surgery. About 100 adults will be observed before, during, and up to 10 days after surgery. The goal is to better identify high-risk patients so that prevention can …