POSTOPERATIVE DELIRIUM

This study tests whether doing simple, home-based brain exercises for a few weeks before heart surgery can help prevent confusion (delirium) and long-term memory problems after the operation. Researchers will enroll 100 adults scheduled for elective heart surgery. Half will do th…

This study tests whether a sleep medication called daridorexant can prevent delirium (sudden confusion) after heart surgery. About 80 adults aged 60 and older having valve or bypass surgery will take either the drug or a placebo for three nights after surgery. Researchers will ch…

This study tests whether relaxation techniques like virtual reality and binaural beats, given before heart surgery, can lower stress and prevent postoperative delirium (sudden confusion) and cognitive decline (memory or thinking problems). About 125 adults having elective heart s…

This study tests whether a digital sleep program (a mobile app and a wrist-worn activity tracker) can help older adults sleep better and protect their brain health after hip or knee replacement surgery. About 50 people aged 65 and older with mild insomnia will use the app before …

This study compares two sedative drugs, dexmedetomidine and midazolam, to see which one better prevents confusion (delirium) after coronary artery bypass surgery. About 60 adults having elective heart bypass will take part. The goal is to find out which drug leads to fewer cases …

This study looks at whether a score based on routine blood tests (the Naples Prognostic Score) can predict postoperative delirium—sudden confusion—in older adults after hip fracture surgery. Researchers will follow 168 patients aged 60 and older to see if the score identifies tho…

This study watches 100 adults aged 60 and older during major non-cardiac surgery to learn how to set the best blood pressure for brain health. Researchers use non-invasive forehead monitors to track brain activity and oxygen levels. The goal is to see if these monitors can help t…

This study looks at 500 adults having heart surgery to see if keeping blood pressure within each person's safe range (using brain monitors) can lower the chance of confusion, stroke, or memory problems after surgery. Participants will have their brain activity tracked during the …

This study follows 1500 adults having planned heart surgery to learn why some become confused or delirious afterward. Researchers will track patients before and after surgery to find risk factors and see how delirium affects recovery over time. The goal is to better predict and p…

This study looks at whether feeling distressed before surgery increases the risk of confusion (delirium), pain, and longer hospital stays in older adults having major orthopedic surgery. Researchers will measure distress levels before surgery and track outcomes in 150 patients ag…

This study is looking at whether simple blood tests taken before surgery can help predict which children might become confused or agitated after waking up from anesthesia. The study will include 140 children aged 2 to 12 who are having circumcision. Researchers will check for cer…

This study watches 270 older adults (65+) having non-heart surgery to see how often they become confused or delirious afterward. Researchers will track risk factors like age, health, and frailty, and measure how delirium affects recovery. No treatments are tested—the goal is to l…

This study looks at whether certain proteins in the blood can help predict if older adults with diabetes will experience confusion (delirium) after surgery. Researchers will measure these proteins before surgery in 180 participants aged 65 and older. The goal is to find early war…