PORTAL HYPERTENSION

This study follows 132 people aged 18-85 who need a device called the Cera Vascular Plug to block blood flow in certain blood vessels. The plug is used for conditions like aneurysms (bulging blood vessels) or abnormal connections between arteries and veins. The goal is to confirm…

This study compares two drugs, terlipressin and somatostatin, to see which better lowers high blood pressure in the liver's main vein during a living-donor liver transplant. High pressure can cause dangerous bleeding, so finding the best drug may improve safety. About 50 adults w…

This study tests whether adding the blood thinner apixaban to the standard drug carvedilol can prevent serious problems like bleeding, fluid buildup, and liver failure in people with cirrhosis. About 220 adults with liver scarring and high blood pressure in the liver will take ei…

This study collects blood, tissue, and imaging data from 1,000 people with portal hypertension (high blood pressure in the liver) to create a biobank. Researchers will use this information to better understand why some patients experience severe bleeding from veins in the esophag…

This study looks at a rare liver condition called Porto-Sinusoidal Vascular Disease (PSVD) that causes high blood pressure in the liver's main vein, leading to serious problems like bleeding or fluid buildup. Researchers want to see how well a procedure called TIPS works for thes…

This study follows 10,000 people with advanced chronic liver disease to track their health over time. Researchers will collect medical data and samples like blood, urine, and tissue to better understand how cirrhosis progresses. The goal is to learn more about the disease, not to…

This study looks at why blood clots form in the portal vein (a major liver vein) in people with liver cirrhosis. Researchers will take blood samples from two different veins during a routine procedure called TIPS to compare clotting activity. The goal is to understand how local a…

This study is testing whether a special 3D MRI scan (called 3D-MRE) can accurately measure liver pressure in people with cirrhosis or advanced liver disease. Currently, doctors must insert a thin tube into a neck vein to measure this pressure. If the scan works, it could offer a …