10,000 liver patients enrolled in landmark Long-Term study
NCT ID NCT03267615
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 10,000 people with advanced chronic liver disease at Vienna General Hospital. Researchers will track their health over time, collect blood, urine, and tissue samples, and record complications like bleeding or liver failure. The goal is to better understand how cirrhosis progresses and what factors affect survival without a transplant.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better predict and manage liver cirrhosis complications.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may take years to emerge.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2017
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patient with advanced chronic liver disease diagnosed and/or treated at the Medical University of Vienna will be screened for inclusion/exclusion criteria.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>18 years and \<100 years * Diagnosis of advanced chronic liver disease (by liver stiffness ≥10kPa, HVPG\>5mmHg or Histology F3/F4) * Written informed consent Exclusion Criteria: * Withdrawal of written informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medical University of Vienna
RECRUITINGVienna, 1090, Austria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Gut bacteria in a capsule: a new attempt to calm a brain complication of cirrhosis
- Ultrasound may replace invasive test for dangerous liver complication
- Can a digital platform catch liver cancer sooner?
- Can a Two-Drug combo keep cirrhosis patients out of the hospital?
- A needle through the gut could replace the standard liver pressure test
- Spleen surgery may reshape cholesterol in cirrhosis