PORTAL HYPERTENSION

This study looks at a new way to do liver transplants for people with severe portal hypertension, a condition where high blood pressure in the liver causes serious problems. Instead of using a full-sized liver, doctors will use a smaller piece (small-for-size graft) placed alongs…

This observational study follows 11 people with chronic hepatitis B and D coinfection and liver cirrhosis who are already taking Bulevirtide. Researchers want to see if the drug reduces portal hypertension (high blood pressure in the liver), which is a major cause of complication…

This study tests whether beta-blockers, a type of blood pressure medicine, can reduce the risk of bleeding from small varices in people with cirrhosis and portal hypertension. About 763 adults with small varices will receive either beta-blockers or a placebo for up to 3 years. Th…

This study follows 852 adults with liver cirrhosis who are scheduled for a TIPS procedure, a shunt placed in the liver to relieve dangerous high blood pressure. Researchers will collect information from standard medical care over 5 years to learn how to best use TIPS and reduce c…

This study looks at how social factors like income and neighborhood, plus financial burdens like out-of-pocket costs, affect people with cirrhosis and their caregivers. Researchers will ask about work productivity, medication changes, and financial distress. The goal is to better…