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New MRI scan could replace needle test for liver patients

NCT ID NCT05475015

First seen Feb 12, 2026 · Last updated Jun 22, 2026 · Updated 14 times

Summary

This study is testing whether a special MRI scan called 3D-MRE can accurately detect high blood pressure in the liver (portal hypertension) caused by cirrhosis or advanced liver disease. Currently, doctors use an invasive catheter procedure (HVPG) to measure this pressure. The study will enroll 150 adults with chronic liver disease who need an HVPG test, and compare the 3D-MRE results to the standard catheter measurement. If 3D-MRE works well, it could offer a safer, non-invasive way to diagnose and manage these conditions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shengjing Hospital

    RECRUITING

    Shenyang, Liaoning, 210000, China

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

3D-MRE (a special MRI scan)

What this could lead to

If successful, this could provide a non-invasive way to diagnose and manage portal hypertension in cirrhosis patients, reducing the need for risky catheter procedures.

What could go wrong

This is an early diagnostic study with 150 participants, so results may not apply to all patients. The accuracy of 3D-MRE might not be high enough to replace current methods.

Conditions

The condition(s) this trial relates to.

cirrhosis of liver portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.