New MRI scan could replace needle test for liver patients
NCT ID NCT05475015
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a special MRI scan called 3D-MRE can accurately detect high blood pressure in the liver (portal hypertension) caused by cirrhosis or advanced liver disease. Currently, doctors use an invasive catheter procedure (HVPG) to measure this pressure. The study will enroll 150 adults with chronic liver disease who need an HVPG test, and compare the 3D-MRE results to the standard catheter measurement. If 3D-MRE works well, it could offer a safer, non-invasive way to diagnose and manage these conditions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 3D-MRE (a special MRI scan)
- What this could lead to
- If successful, this could provide a non-invasive way to diagnose and manage portal hypertension in cirrhosis patients, reducing the need for risky catheter procedures.
- What could go wrong
- This is an early diagnostic study with 150 participants, so results may not apply to all patients. The accuracy of 3D-MRE might not be high enough to replace current methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shengjing Hospital
RECRUITINGShenyang, Liaoning, 210000, China
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