Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could the Body's largest vein replace a Hard-to-Reach one for liver pressure checks?

NCT ID NCT07703540

Diagnosis Sponsor: University Hospital Muenster Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether the inferior vena cava (the body's main vein) can serve as a reliable reference point for measuring blood pressure in the liver during an endoscopic ultrasound. Normally, doctors use a hepatic vein for this, but in people with advanced liver scarring, those veins can be twisted and hard to reach. By comparing pressure readings from both veins in 40 adults already scheduled for the procedure, researchers aim to see if the two measurements are interchangeable. If so, it could lead to a safer, more accessible diagnostic method for portal hypertension.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could make measuring liver blood pressure safer and more reliable for patients with advanced cirrhosis and complex vein anatomy.
What could go wrong
This is a small, early study with only 40 participants. The inferior vena cava may not provide interchangeable pressure readings, and the procedure carries risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Feb 2026

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of consecutive adult patients ($\\ge18$ years) undergoing a clinically indicated EUS-PPG measurement (e.g., for liver disease evaluation, fibrosis staging, or portal hypertension assessment).

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Consecutive adult patients (≥18 years) undergoing clinically indicated EUS-guided portal pressure gradient measurement Exclusion Criteria: * severe coagulopathy (INR \>2.0), thrombocytopenia (\<50,000/µL) * large-volume ascites * gastric varices precluding safe vascular puncture * known hepatic vein thrombosis or Budd-Chiari syndrome * altered IVC anatomy such as patients after liver transplantation with piggy-back anastomosis * contraindication to upper gastrointestinal endoscopy or sedation * pregnancy

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cirrhosis are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis liver disorder portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cirrhosis Liver disease chronic Portal hypertension

Contacts and locations

Locations

  • University Hospital Muenster

    Münster, North Rhine-Westphalia, 48149, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.