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Could a dissolvable sponge replace medical glue for dangerous stomach vein bleeds?

NCT ID NCT07699354

Not yet recruiting Disease control Sponsor: Unity Health Toronto Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial tests whether an absorbable gelatin sponge works as well as cyanoacrylate glue for closing off enlarged stomach veins that can bleed. Both treatments are delivered via endoscopy with small coils. Participants are adults with a history of bleeding from these veins, and they will be followed for up to a year to see which approach more effectively stops blood flow in the vein.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cyanoacrylate glue and absorbable gelatin sponge
What this could lead to
If the absorbable gelatin sponge works as well as the glue, it could offer a safer, equally effective option for treating bleeding stomach veins.
What could go wrong
This is a small, early-stage trial with only 64 participants, so results may not apply to everyone. The gelatin sponge might not close off the veins as effectively as the glue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

esophageal varices esophageal varices with bleeding portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRIC VARICES GASTRIC VARICES BLEEDING PORTAL HYPERTENSION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Michael's Hospital - Unity Health Toronto

    Toronto, Ontario, M5B 1W8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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