PERSISTENT ATRIAL FIBRILLATION

This study compares two techniques—radiofrequency and pulse field ablation—to treat persistent atrial fibrillation, a condition where the heart beats irregularly. Researchers will check which method better isolates the areas causing the problem and keeps the heart in normal rhyth…

This study tests if adding extra ablation to the standard procedure helps people with persistent atrial fibrillation (a type of irregular heartbeat) stay in normal rhythm longer. About 206 adults will get either standard ablation or standard plus additional ablation, using a newe…

This study tests a catheter-based procedure to treat people with persistent or long-standing atrial fibrillation (an irregular heartbeat) who also have an enlarged left atrium. The procedure uses targeted energy to isolate areas in the heart that cause the abnormal rhythm. The ma…

This study compares a new procedure called pulsed field ablation (PFA) to standard anti-arrhythmic drugs as the first treatment for people with persistent atrial fibrillation (a type of irregular heartbeat). About 484 participants will be randomly assigned to receive either the P…

This study follows 200 adults with persistent atrial fibrillation (a type of irregular heartbeat lasting more than 7 days but less than a year) who are treated with the Sphere-9 catheter and Affera ablation system. The goal is to see if the procedure safely prevents the return of…

This study tests a new device that uses short bursts of electricity to treat atrial fibrillation (AFib), a condition causing an irregular heartbeat. About 549 people with symptomatic AFib will receive the procedure. The goal is to see if it safely stops abnormal heart rhythms for…

This study compares two ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat). One method isolates the pulmonary veins, while the other also targets additional areas in the heart. The goal is to see which approach better prevents the r…

This study tests a new catheter system that uses pulsed electric fields to treat atrial fibrillation, a common heart rhythm problem. About 275 adults with either occasional or persistent AFib will undergo a standard ablation procedure using this device. The goal is to see if it s…

This study compares different catheter ablation strategies in 300 adults aged 18-80 who have both persistent atrial fibrillation (an irregular heartbeat) and heart failure. The goal is to see which approach best reduces the risk of death, hospitalization, or urgent care due to wo…

This study tests a new system that uses pulsed field ablation to treat atrial fibrillation, a common heart rhythm problem. About 300 people with symptoms that haven't improved with medication will receive the procedure. The goal is to see if it safely and effectively restores a n…

This study follows 400 adults with persistent atrial fibrillation (a type of irregular heartbeat) who are treated with a procedure called cryoablation. The procedure uses a special catheter to freeze small areas of heart tissue that cause the abnormal rhythm. Researchers want to …

This early study tests a new balloon-shaped catheter that uses pulsed electric fields to treat persistent atrial fibrillation, a type of irregular heartbeat. 34 adults aged 18-75 with persistent AF will undergo the procedure and be followed for 12 months to check safety and how w…

This pilot study tests whether advanced ECG mapping, MRI, and PET scans can better identify the heart tissue causing persistent atrial fibrillation (AFib). Researchers will use these images to guide a personalized catheter ablation procedure in 52 adults with persistent AFib. The…