PERIODONTAL DISEASES

This study tests two ways to improve oral health in older adults who have both gum disease and mild cognitive impairment. One group uses a special light device plus a manual toothbrush, another uses a powered toothbrush, and a third uses a standard soft toothbrush. Researchers wi…

This study looks at how well 3D-printed, custom-fit bone grafts work for rebuilding jawbone lost to gum disease. Researchers will check if dental implants placed in the grafted area stay stable and measure how much the graft shrinks over time. The study involves 100 healthy adult…

This study is developing a new, non-invasive test that uses saliva and artificial intelligence to detect gum disease (periodontitis) early. Researchers will collect saliva from 200 adults—some with gum disease and some healthy—and use a special sensor and AI to see if it can accu…

This study aims to validate an Italian version of a questionnaire used to screen for periodontitis (severe gum disease). Researchers will test how accurately the questionnaire identifies people with and without the condition, compared to a standard dental exam. About 495 adults a…

This study tests a new program to improve oral health in pregnant women in Bangladesh, where over 95% have gum disease. 688 pregnant women will either receive standard care or extra education sessions, a special tooth-brushing technique, and weekly text reminders. Researchers wil…

This study looks at whether certain substances in saliva and fluid around dental implants can help detect and monitor bone loss and inflammation in people with peri-implantitis. Researchers will compare these markers in 80 adults: those with peri-implantitis, those with regular g…

This study looks at how the edge of a clear aligner (the part near the gums) affects the bacteria living in the gum pocket. 39 people finishing their orthodontic treatment will wear aligners with two different edge designs at the same time. The goal is to see if one design leads …

This study looks at the teeth, mouth, and face of people with Mowat-Wilson syndrome, a rare genetic condition. Researchers will check for cavities, gum disease, and facial differences, and ask about quality of life. No treatments are tested—only observations are made. About 25 pe…

This study aims to find out if tiny plastic particles, called microplastics, are present in the deep gum pockets of people with severe periodontitis (stage III or IV). Researchers will collect plaque from 25 adults who have not yet started gum treatment. The goal is to measure ho…

This study looks at three techniques for removing a tiny bit of enamel between teeth to make room during clear aligner (like Invisalign) treatment. Seventy-five adults will be randomly assigned to one of three methods: manual strips, motor-driven strips, or abrasive discs. The ma…

This study will check if teeth that get more chewing force are more likely to have gum disease. About 50 adults with natural teeth or fixed dental work will be observed. Researchers will use special software to measure bite forces and compare them to gum health. The goal is to un…

This study follows 100 adults with and without gum disease for two years to see if certain substances in saliva can predict who will develop or worsen gum problems. Participants provide saliva and plaque samples at yearly visits while researchers track their gum health. No treatm…