OBSTRUCTIVE SLEEP APNEA (OSA)

This study looks at how safe and effective Inspire therapy is for people with severe obstructive sleep apnea (OSA) who also have a higher body weight. Researchers will track side effects and changes in sleep apnea severity over time. The study involves 70 adults who cannot use st…

This study looks at whether telehealth care, including a human sleep navigator, works as well as private sector care for military members with obstructive sleep apnea. Researchers will compare sleep quality, treatment adherence, and costs in 160 participants. The goal is to impro…

This study looks at whether surgery to remove tonsils and adenoids can slow down or prevent scoliosis (curved spine) in children aged 6 to 15 who have mild sleep-disordered breathing. Researchers will measure spine curves and quality of life in 160 children over time. The goal is…

This study aims to improve treatment for obstructive sleep apnea (OSA) in people with Down syndrome by matching therapy to each person's specific cause of OSA. Researchers will compare a standard medication combination (atomoxetine and oxybutynin) with a personalized approach tha…

This study tests a small device implanted in the neck that stimulates a nerve to keep the airway open during sleep. It is for adults with moderate to severe obstructive sleep apnea who cannot use a CPAP machine. The goal is to see if the device is safe and improves breathing and …

This study is testing whether simple measurements like facial scans, videos of you speaking and blinking, and heart rate changes can help doctors diagnose obstructive sleep apnea (OSA). Researchers will collect data from 800 adults who do not already have an OSA diagnosis. The go…

This study explores whether short smartphone videos recorded by parents can accurately screen for moderate-to-severe obstructive sleep apnea (OSA) in children. OSA causes breathing to stop during sleep and can lead to health problems if untreated. The study will enroll 625 childr…

This study is testing whether a combination of noninvasive sensors—like a smart stethoscope, pulse oximeter, and motion tracker—can accurately estimate the severity of obstructive sleep apnea. Researchers will enroll 150 adults who are already scheduled for an overnight sleep stu…

This study checks if a portable sleep monitor can accurately detect obstructive sleep apnea in children with autism spectrum disorder. Researchers will compare the portable device's results with the standard in-lab sleep test. The study involves 20 children aged 6 to 18 who are h…

This study tests whether using a CPAP machine that sends data to doctors remotely helps people with severe sleep apnea use it more regularly. Two hundred adults who are new to CPAP will be split into two groups: one gets standard care, the other gets a CPAP with remote monitoring…

This study tests whether simple exercises involving drinking water and breathing can improve sleep quality in 60 adults with obstructive sleep apnea (OSA). Some participants have also had a traumatic brain injury. The goal is to see if these exercises reduce breathing pauses duri…

This study looks at whether a dental mouthpiece works as well as a CPAP machine to improve thinking and memory in people with sleep apnea who also have mild memory problems. About 260 adults aged 45 and older with moderate-to-severe sleep apnea will be randomly assigned to use ei…

This study tests whether a high-flow nasal cannula (a device that delivers warm, moist oxygen) can prevent dangerously low oxygen levels during sedated gastrointestinal endoscopy in people at high risk for obstructive sleep apnea. Researchers will enroll 600 adults with a STOP-Ba…

This study tests a digital program that uses facial recognition to guide mouth and throat exercises for people with mild to moderate sleep apnea. The exercises aim to strengthen airway muscles and improve breathing during sleep. About 60 adults who cannot or will not use standard…

This study is a registry that follows 1000 people who have or will receive the Inspire implant for obstructive sleep apnea. Researchers will track how well the device works and how consistently patients use it over time during regular clinic visits. No extra tests or treatments a…

This study looks at whether removing extra fluid from the body helps improve sleep apnea in adults hospitalized with heart failure. About 50 participants will wear a sleep monitor before and after fluid removal. Researchers will measure changes in sleep apnea severity and see if …

This study is testing whether mild electrical stimulation of the tongue and chin muscles can help people at risk for sleep apnea. 28 adults will receive five different stimulation frequencies in one visit. Researchers will measure changes in tongue muscle thickness, length, and s…

This study aims to test a new classification system for obstructive sleep apnea that considers both daytime sleepiness and cardiovascular risk. Researchers will follow 1800 adults aged 40 and older who are newly diagnosed with sleep apnea. The goal is to see if this new system be…

This study looks at two common ways to stop teeth from shifting in people who use a special mouthpiece (MAD) for sleep apnea or snoring. About 30 adults will either wear a clear aligner each morning or do jaw exercises for 3 months. The goal is to see which method better prevents…

This study looks at how the tongue changes in children and teens with obesity after a 30-week weight loss program. Researchers will use ultrasound to measure tongue fat, shape, and stiffness, and see how these relate to sleep apnea. About 100 participants aged 6 to 18 will be sca…