OBSTRUCTIVE SLEEP APNEA (OSA)

This study is testing whether a program of mouth, tongue, and breathing exercises, called myofunctional therapy, can help children aged 6-12 with obstructive sleep apnea (OSA). 174 children will be randomly assigned to either do the 24-week exercise program with remote guidance o…

This study is testing a new type of nighttime mouthpiece designed to help control obstructive sleep apnea (OSA). The device gently and gradually moves the lower jaw forward during sleep to keep the airway open. Researchers will measure its effects on breathing, oxygen levels, and…

This study is testing if wearing a Garmin smartwatch can help people with moderate to severe sleep apnea use their CPAP breathing machine more often. Researchers will compare 80 first-time CPAP users in Thailand, with half using the watch's sleep and health data for motivation an…

This study is testing a new software tool designed to help doctors quickly set up CPAP machines for people newly diagnosed with obstructive sleep apnea. The software uses information about the patient to recommend personalized pressure settings, with the goal of being as effectiv…

This study aims to find a better way to treat sleep apnea in people with Down syndrome. It will test if choosing a treatment based on a person's specific breathing problems works better than giving everyone the same two-drug combination. Researchers will enroll 200 children and a…

This study is testing a smart mattress designed to diagnose obstructive sleep apnea (OSA) from the comfort of a patient's home. Researchers will compare the mattress's readings to the results from the standard, more invasive hospital sleep study (polysomnography) in 500 people. T…

This study is testing whether a special program for couples can help African American patients with moderate-to-severe sleep apnea use their CPAP machines more regularly. The program includes virtual couples therapy, peer support groups, and text message reminders. Researchers wi…

This study compares two ways to manage pain after tonsil and adenoid removal in children with mild to moderate sleep apnea. It tests if a combination of non-opioid medications works as well as the opioid fentanyl. The goal is to provide effective pain relief while reducing risks …

This study aims to understand why people with obstructive sleep apnea (OSA) might have a harder time fighting infections. Researchers will compare blood samples from 80 people with moderate-to-severe OSA and 40 people without it, looking at how their immune cells respond. They wi…

This study aims to understand if having obstructive sleep apnea (OSA) increases a person's risk for high blood pressure in the lungs, known as pulmonary hypertension. Researchers will observe 55 adults already diagnosed with sleep apnea, using heart ultrasound scans to measure lu…

This study aims to understand how opioid pain medications affect breathing during sleep. Researchers will compare healthy volunteers with people who have obstructive sleep apnea. Participants will receive either morphine or a placebo during monitored sleep to measure breathing ch…