Breathing test may replace overnight sleep studies for CPAP settings
NCT ID NCT07554430
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a quick, non-invasive breathing test called impulse oscillometry (IOS) can help doctors find the right pressure settings for sleep apnea machines. Currently, patients often need an overnight sleep study to determine the correct pressure. The study will include 92 adults with moderate-to-severe obstructive sleep apnea and compare the breathing test results with the pressure settings determined during a standard sleep study.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simpler way to set sleep apnea machines without needing an overnight sleep study.
- What could go wrong
- This is an early observational study with only 92 people. The breathing test may not accurately predict pressure settings for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 92 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults with moderate-to-severe obstructive sleep apnea (OSA) undergoing PAP titration and IOS testing at Hatay Mustafa Kemal University.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 80 years * Diagnosed with obstructive sleep apnea (OSA) by overnight polysomnography (PSG) * Apnea-hypopnea index (AHI) ≥ 15 * Undergoing positive airway pressure (PAP) titration (CPAP or BPAP) * Able to perform impulse oscillometry (IOS) test * Provided written informed consent Exclusion Criteria: * Central sleep apnea * Neuromuscular disease or restrictive lung disease * Recent upper airway infection (\< 2 weeks) * Incomplete PSG or IOS data * Inability to cooperate with testing procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hatay Mustafa Kemal University
Antakya, Hatay, 31001, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a weekly phone call keep sleep apnea patients on CPAP?
- A smart neck brace may replace CPAP for sleep apnea
- A blood test for liver trouble may flag hidden risk in sleep apnea patients
- Blood oxygen dips may reveal who stays on CPAP
- Can a simple questionnaire improve sleep apnea treatment?