OBESITY, MORBID

This pilot study is testing whether a non-surgical procedure to reduce stomach size is safe and effective for weight loss in adolescents with obesity. The procedure, called Endoscopic Sleeve Gastroplasty (ESG), is performed through the mouth using a special device. Researchers wi…

This early study is testing whether a small, implanted brain stimulator can help people who struggle with severe loss of control over eating. The device, similar to those used for epilepsy, is being tried in six people with severe obesity who have not been helped by surgery or ot…

This study compares two telemedicine approaches to help rural residents with obesity manage their weight over 18 months. One approach uses quarterly doctor visits, while the other adds group lifestyle coaching sessions via Zoom. Researchers want to see which method helps people l…

This study compares two types of intestinal bypass surgery performed after a previous stomach reduction surgery for severe obesity. Researchers want to see if a newer, simpler surgical connection causes fewer digestive problems and nutritional deficiencies than the standard metho…

This study is testing if a safe, injectable dye can help surgeons see blood flow better during a common weight-loss surgery. The goal is to see if this helps reduce complications like ulcers, leaks, or narrowing at the surgical connection. About 300 patients having this surgery w…

This study is testing an 8-week online program designed for couples where one person had weight loss surgery 1-3 years ago. The program uses positive psychology activities, like expressing gratitude and setting goals, to help improve mood, resilience, and relationship satisfactio…

This study aims to understand if bariatric (weight-loss) surgery can help improve memory and thinking skills in people with obesity. Researchers will enroll 9,500 participants who have obesity and either have or are at risk for cognitive issues. They will compare test results bef…

This study analyzes existing medical records from 8,000 people who had weight-loss surgery at a specific medical center. Researchers are looking back at the data to understand how well different surgeries work for severe obesity. They want to learn about weight loss results, surg…

This study aims to collect and store blood, urine, and tissue samples from 500 adults with obesity. The goal is to create a research bank to help scientists understand why people gain weight, why treatments sometimes fail, and why weight is often regained. This knowledge could le…

This study aims to collect long-term data on 5,000 patients who have had endoscopic or surgical weight loss procedures. Researchers will track weight changes, health improvements, side effects, and costs over 10 years to better understand which treatments work best. The goal is t…