OBESITY, MORBID
Clinical trials for OBESITY, MORBID explained in plain language.
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Weight-loss drug tirzepatide shows promise for post-surgery weight regain
Disease control CompletedThis study looked at how the drug tirzepatide works in real-world settings for two groups: people who regained weight after bariatric surgery and people with obesity preparing for surgery. Researchers tracked weight and health changes over six months in 254 adults. The goal was t…
Matched conditions: OBESITY, MORBID
Sponsor: Azienda Sanitaria Locale Napoli 2 Nord • Aim: Disease control
Last updated May 26, 2026 11:33 UTC
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New surgery may beat gold standard for weight loss
Disease control CompletedThis study compares two types of weight-loss surgery for people with severe obesity: a newer procedure called SADI-S and the standard RYGB. About 382 adults will be randomly assigned to one surgery and followed for 2 years to see which leads to greater weight loss and fewer compl…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated May 26, 2026 11:25 UTC
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New surgical wrap aims to boost weight loss and stop bile reflux after gastric bypass
Disease control CompletedThis study tested a new surgical method called FundoRing, where surgeons wrap part of the stomach to prevent weight regain and bile reflux after gastric bypass. 1000 adults with obesity were randomly assigned to get either the new wrap or the standard bypass. The goal was to see …
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: The Society of Bariatric and Metabolic Surgeons of Kazakhstan • Aim: Disease control
Last updated May 26, 2026 11:24 UTC
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Simple surgical addition may ease heartburn after Weight-Loss surgery
Disease control CompletedThis study looked at whether adding a small repair for acid reflux during weight-loss surgery can reduce heartburn symptoms afterward. Fifty adults with severe obesity but no hiatal hernia were split into two groups: one got standard sleeve gastrectomy, the other got the same sur…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Van Training and Research Hospital • Aim: Disease control
Last updated May 26, 2026 11:24 UTC
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Could a diabetes pill combo help people with severe obesity shed more weight?
Disease control CompletedThis study looked at whether adding dapagliflozin to metformin helps people with severe obesity (BMI 40+) and prediabetes or type 2 diabetes lose more weight than metformin alone. About 160 participants took either the combination or metformin only for up to 12 months. The goal w…
Matched conditions: OBESITY, MORBID
Phase: PHASE2, PHASE3 • Sponsor: Centro Medico Nacional Siglo XXI IMSS • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New magnet device aims to boost weight loss after failed surgery
Disease control CompletedThis study tested a new tool that uses magnets to create connections in the intestines, helping people with severe obesity who didn't lose enough weight after their first surgery. 28 adults took part to see if the device was safe and worked as intended. The goal was to improve we…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: GI Windows, Inc. • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New pain block study aims to cut opioid use after Weight-Loss surgery
Symptom relief CompletedThis study tested two different ultrasound-guided nerve blocks to manage pain after laparoscopic sleeve gastrectomy in 40 obese patients. The goal was to see which block provides longer pain relief and reduces the need for opioids, which can be risky in this group. Both technique…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Kasr El Aini Hospital • Aim: Symptom relief
Last updated May 26, 2026 11:36 UTC
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Ultrasound may help super obese moms get safer spinal anesthesia
Symptom relief CompletedThis study tested whether using ultrasound to guide spinal anesthesia is better than the traditional touch-based method in super obese women (BMI 50 or higher) having a planned C-section. Sixty women took part, and the main goal was to see which method led to a successful needle …
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Karaman Training and Research Hospital • Aim: Symptom relief
Last updated May 26, 2026 10:35 UTC
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New nerve block slashes opioid use after sleeve gastrectomy
Symptom relief CompletedThis study tested whether a special nerve block (RIB block) could reduce pain and the need for strong painkillers after laparoscopic sleeve gastrectomy, a common weight-loss surgery. Fifty-six adults with severe obesity were randomly assigned to receive either the nerve block plu…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Samsun University • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Bring a buddy to boost bariatric results?
Knowledge-focused CompletedThis study looked at whether having a partner or support person attend bariatric surgery clinic visits helps patients lose more weight and stick to healthy habits. 63 adults preparing for or recovering from bariatric surgery were split into groups that either brought a support pe…
Matched conditions: OBESITY, MORBID
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 11:25 UTC
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Sleeve gastrectomy alters appetite hormone levels, small study finds
Knowledge-focused CompletedThis study looked at 36 adults with severe obesity who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured blood levels of Phoenixin-14, a hormone that may affect appetite, before and after surgery. The goal was to see if the surgery changes t…
Matched conditions: OBESITY, MORBID
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Bariatric Surgery's hidden metabolic shifts revealed
Knowledge-focused CompletedThis study measured amino acid levels in the blood of 50 people before and after bariatric surgery, comparing them to 50 healthy individuals. The goal was to understand how surgery affects metabolism. Results show clear changes in amino acid profiles over three months, linked to …
Matched conditions: OBESITY, MORBID
Sponsor: Harran University • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC
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Super obese moms: tailored spinal dose improves C-Section safety
Knowledge-focused CompletedThis study looked at 45 super obese women (BMI over 50) having a planned C-section to find the best dose of spinal anesthesia. The goal was to ensure the anesthesia worked well without needing extra pain medicine during surgery. The results help doctors give safer, more effective…
Matched conditions: OBESITY, MORBID
Phase: PHASE4 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC