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New pain block may cut opioid use after gastric sleeve surgery

NCT ID NCT07253610

First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 26 times

Summary

This study tested whether a specific nerve block, called a rectointercostal fascial plane block, could reduce pain and the need for strong painkillers after laparoscopic sleeve gastrectomy. Fifty-six adults undergoing weight-loss surgery were randomly assigned to receive either the nerve block plus standard pain control or standard pain control alone. The main goal was to measure total opioid use in the first 24 hours after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Istinye University Faculty of Medicine, Medical Park Gaziosmanpasa Hospital

    Istanbul, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

local anesthetic (nerve block)

What this could lead to

If effective, this nerve block could reduce the need for strong painkillers after weight-loss surgery, leading to faster recovery and fewer side effects.

What could go wrong

This is a small, completed study with 56 participants. The nerve block may not work for everyone, and there is a small risk of complications like infection or bleeding from the injection.

Conditions

The condition(s) this trial relates to.

morbid obesity Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.