NAFLD
Clinical trials for NAFLD explained in plain language.
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Can a walk or a gym workout, plus mediterranean diet, fight inflammation from fatty liver?
Disease control Recruiting nowThis study aims to see if adding exercise to a healthy Mediterranean diet is better than diet alone for reducing body-wide inflammation in adults with obesity and non-alcoholic fatty liver disease (NAFLD). Researchers will compare two different exercise programs—outdoor walking a…
Matched conditions: NAFLD
Phase: NA • Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Vitamin B3 trial aims to halt liver damage
Disease control Recruiting nowThis study is testing whether a form of vitamin B3 called nicotinamide can stop or even reverse liver scarring (fibrosis) in people with fatty liver disease. About 30 overweight or obese adults will take either nicotinamide or a placebo pill daily for one year. Researchers will u…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Old heart drug could be new hope for millions with fatty liver
Disease control Recruiting nowThis study is testing if digoxin, a medication used for heart conditions, can help treat a serious liver disease called NASH (now called MASH). Researchers will give 144 people with NASH either digoxin or a placebo pill daily for 24 weeks to see if it reduces liver inflammation a…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Scientists test exercise as medicine for silent liver epidemic
Disease control Recruiting nowThis study aims to find the most effective 'dose' of exercise for treating fatty liver disease (NAFLD/NASH), which has no approved drug cure. Researchers will test different exercise amounts in 45 sedentary adults with the disease to see which best reduces liver fat. The goal is …
Matched conditions: NAFLD
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC
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VA launches new program to catch silent liver disease before It's too late
Diagnosis Recruiting nowThis study is testing a new care system designed to improve how fatty liver disease (NAFLD) is found and managed in Veterans. The system automatically flags at-risk patients, calculates their risk scores, and educates their primary care doctors. Researchers will compare this new …
Matched conditions: NAFLD
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Diagnosis
Last updated Apr 03, 2026 19:40 UTC
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New test strategies could spare thousands from painful liver biopsies
Diagnosis Recruiting nowThis study aims to find the best non-invasive testing strategy to diagnose advanced liver scarring (fibrosis) in people with fatty liver disease (NAFLD). Researchers will compare two different step-by-step approaches that combine simple blood tests with specialized scans to accur…
Matched conditions: NAFLD
Phase: NA • Sponsor: University Hospital, Angers • Aim: Diagnosis
Last updated Mar 23, 2026 15:17 UTC
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Scientists grow Mini-Livers to crack code of silent epidemic
Knowledge-focused Recruiting nowThis study aims to better understand how a common genetic variant contributes to the development of a serious form of fatty liver disease. Researchers will create 3D models, called 'assembloids,' from liver tissue donated by 60 participants. These lab-grown models will be used to…
Matched conditions: NAFLD
Phase: NA • Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Unlocking the genetic code of fatty liver disease
Knowledge-focused Recruiting nowThis study aims to understand why some people with fatty liver disease develop serious liver or heart complications while others do not. Researchers will follow 2,500 middle-aged blood donors who are overweight or have related health issues. They will use genetic tests, blood mar…
Matched conditions: NAFLD
Phase: NA • Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC