NAFLD

This study is testing whether placing a temporary balloon in the stomach helps people with fatty liver disease. Researchers will follow 200 obese patients for at least one year after the balloon is placed to see if they lose weight and if their liver health improves. The goal is …

This study is testing if a common diabetes medication, empagliflozin, can prevent or slow the progression of liver scarring (fibrosis and cirrhosis) in people with chronic hepatitis B. The trial involves 106 patients who are already taking standard antiviral drugs but still have …

This study is testing if an 8-week, very low-calorie meal replacement diet can reduce harmful fat and scarring in the livers of people with obesity and non-alcoholic fatty liver disease (NAFLD). Researchers will compare 10 people on the special diet to 10 others on a standard low…

This study is testing whether an investigational drug called efinopegdutide can help treat a serious form of fatty liver disease called MASH that has progressed to cause permanent scarring (cirrhosis). About 80 adults with this condition will receive either the drug or a placebo …

This study is testing a new portable device called LiverScope that could make it easier to diagnose fatty liver disease. Researchers are comparing this new device to standard MRI and ultrasound scans to see if it works just as well. Participants will have one visit where they try…

This study aimed to test a new type of ultrasound device for detecting and measuring fat in the liver. Researchers planned to compare the device's accuracy to the current standard method, an MRI scan. The trial was withdrawn before any participants were enrolled.

This study is testing new MRI and ultrasound scanning methods to accurately measure fat in children's livers. It involves 24 children, both with obesity and with a healthy weight, to see if these scans are practical and reliable. The goal is to improve the tools doctors use to de…

This research study aims to understand how the hormone glucagon affects liver metabolism in people with obesity, type 2 diabetes, and fatty liver disease. Researchers will study 21 participants to measure how glucagon influences the liver's processing of amino acids and fats. The…

This study aims to understand how common fatty liver disease is in people living with HIV. Researchers will enroll 1,250 participants to measure liver fat and identify factors that increase risk, such as genetics, diet, and HIV treatment history. The goal is to fill a critical kn…

This study aims to find out how common fatty liver disease is in people who have type 2 diabetes. Researchers at a hospital in Belgium will use a special scan to check the livers of 385 adult patients with diabetes. The goal is to gather information to better understand the link …

This study aims to understand how fatty liver disease develops and progresses in people living with HIV. Researchers will follow 400 participants for at least one year, using non-invasive scans to measure liver fat and stiffness. The goal is to fill critical knowledge gaps about …