NAFLD
Clinical trials for NAFLD explained in plain language.
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New hope for teens: drug vs. diet battle for PCOS symptoms
Disease control CompletedThis study tested whether a 12-week treatment with the medication semaglutide works better than an active diet program for teenage girls with obesity and PCOS. The main goal was to see which approach more effectively reduces dangerous fat in the liver and improves how the body us…
Matched conditions: NAFLD
Phase: PHASE2, PHASE3 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug trial targets silent liver disease
Disease control CompletedThis study tested whether a drug called elobixibat could help adults with fatty liver disease (NAFLD or NASH). Forty-seven participants were randomly assigned to receive either the drug or a placebo for 16 weeks. Researchers measured changes in liver fat, cholesterol levels, and …
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Albireo • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Could a growth hormone booster shrink dangerous liver fat?
Disease control CompletedThis small pilot study tested whether a drug called ibutamoren could reduce fat buildup in the livers of people with nonalcoholic fatty liver disease (NAFLD). Researchers enrolled 12 generally healthy adults with NAFLD to take the drug for 6 months. The main goal was to see if li…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New combo targets 'Zombie Cells' to fight liver scarring
Disease control CompletedThis study tested whether a combination of two drugs, dasatinib and quercetin, could reduce liver scarring (fibrosis) in people with fatty liver disease. Thirty adults with confirmed liver scarring participated in this early-stage trial. The goal was to see if clearing certain ag…
Matched conditions: NAFLD
Phase: PHASE1, PHASE2 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New drug shows promise against silent liver disease
Disease control CompletedThis study tested whether the drug efinopegdutide could help adults with nonalcoholic steatohepatitis (NASH), a serious form of fatty liver disease. Researchers compared the drug against a placebo in 381 participants over 52 weeks to see if it could clear liver inflammation witho…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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Could a simple blood test replace liver biopsies for diabetes patients?
Diagnosis CompletedThis study aimed to see if two simple blood tests could effectively screen for liver scarring (fibrosis) in people with type 2 diabetes. It involved 722 participants with type 2 diabetes and a higher body weight. The results of the new blood tests were compared against the curren…
Matched conditions: NAFLD
Phase: NA • Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Apr 03, 2026 14:41 UTC
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French team seeks to replace painful liver biopsies with simple scans and blood tests
Diagnosis CompletedThis study aimed to find better, non-invasive ways to check for liver damage in people with fatty liver disease (NAFLD). Researchers enrolled 1,005 patients across France to compare new blood tests and special scans against the standard liver biopsy. The goal was to develop tools…
Matched conditions: NAFLD
Phase: NA • Sponsor: University Hospital, Angers • Aim: Diagnosis
Last updated Apr 02, 2026 14:56 UTC
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Breakthrough scan lets kids breathe easy during liver tests
Diagnosis CompletedThis study tested new MRI scanning technology designed specifically for children. Current liver scans require patients to hold their breath, which is very difficult for kids and infants. The research aimed to develop 'free-breathing' MRI methods to make liver disease diagnosis mo…
Matched conditions: NAFLD
Sponsor: University of California, Los Angeles • Aim: Diagnosis
Last updated Mar 20, 2026 14:47 UTC
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Fatty liver scars may signal hidden heart danger
Knowledge-focused CompletedThis study aimed to understand the link between fatty liver disease and the risk of developing heart disease. Researchers examined 292 patients with fatty liver disease, using non-invasive scans to measure liver scarring and check for early signs of heart artery disease. The goal…
Matched conditions: NAFLD
Sponsor: Clinique Pasteur • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Researchers tally the Real-World cost of a silent liver epidemic
Knowledge-focused CompletedThis study aimed to understand the financial and personal impact of non-alcoholic fatty liver disease (NAFLD) in Belgium. Researchers surveyed 73 adult patients with NAFLD to calculate their healthcare expenses and measure how the disease affected their quality of life. The goal …
Matched conditions: NAFLD
Phase: NA • Sponsor: Hasselt University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Researchers track silent liver disease in diabetic patients
Knowledge-focused CompletedThis study aimed to understand how common and severe fatty liver disease is in people with type 2 diabetes. Researchers followed 317 patients from Swedish primary care clinics for three years, using advanced scans to measure liver fat and scarring. The goal was to learn which pat…
Matched conditions: NAFLD
Sponsor: Linkoeping University • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC