MYELODYSPLASTIC SYNDROME
Clinical trials for MYELODYSPLASTIC SYNDROME explained in plain language.
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New drug combo aims to boost remission in hard-to-treat blood cancers
Disease control Not yet recruitingThis study tests whether adding the drug olutasidenib to standard treatments helps more people with IDH1-mutated acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) achieve remission. About 132 adults with these blood cancers will receive either standard therapy alone …
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 04:20 UTC
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Engineered immune cells take aim at Hard-to-Treat leukemia
Disease control Not yet recruitingThis early-stage trial tests a new treatment for people with acute myeloid leukemia (AML) or high-risk myelodysplastic syndromes (MDS) that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified in a lab to target a protein …
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 26, 2026 04:20 UTC
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New combo therapy aims to boost red blood cells in bone marrow disease
Disease control Not yet recruitingThis study tests whether adding epoetin alfa or emavusertib to luspatercept helps people with low-risk myelodysplastic syndrome and anemia. About 270 adults will receive one of three drug combinations. The goal is to see if these treatments improve red blood cell counts and reduc…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 04:14 UTC
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Exercise-Powered immune cells take on leukemia in first human trial
Disease control Not yet recruitingThis early study tests a new approach using donor immune cells boosted by exercise to prevent or treat leukemia relapse after a stem cell transplant. About 94 people with blood cancers will receive either standard donor cells or these exercise-mobilized cells. The goal is to see …
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: University of Arizona • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Could a common supplement boost blood counts in bone marrow disease?
Disease control Not yet recruitingThis study tests whether a combination of nicotinamide riboside (a form of vitamin B3) and pterostilbene (a plant compound) can safely improve low blood counts in people with certain bone marrow conditions. Ten adults with lower-risk myelodysplastic syndrome or high-risk clonal c…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New drug QUAIL-100 tested in kids with tough leukemia after transplant
Disease control Not yet recruitingThis early-stage study tests a new drug, QUAIL-100, for safety in 12 children and young adults with high-risk acute leukemia or myelodysplastic syndrome who have already had a special type of stem cell transplant. The goal is to see if the drug is safe and to find the right dose.…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: Laguna Biotherapeutics, Inc. • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New hope for older leukemia patients: targeted radiation before transplant may reduce side effects
Disease control Not yet recruitingThis study tests a new way to prepare older patients (50 and older) with leukemia or MDS that has not responded to treatment for a stem cell transplant. Instead of full-body radiation, they receive targeted radiation to the bone marrow and lymph nodes, plus two chemotherapy drugs…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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Could a protein on Pre-Leukemia cells lead to a new treatment?
Knowledge-focused Not yet recruitingThis study looks at a protein called IL-1RAP found on certain blood cells in people with myelodysplastic syndromes (MDS), a pre-leukemia condition. Researchers want to see if this protein can be targeted by a special immune therapy (CAR-T cells) to kill the diseased cells. They w…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: NA • Sponsor: University Hospital, Grenoble • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Scientists study immune cells to unlock better leukemia monitoring
Knowledge-focused Not yet recruitingThis study collects blood and bone marrow samples from 55 adults with acute myeloid leukemia, acute lymphoblastic leukemia, or myelodysplastic syndrome. Researchers will analyze natural killer (NK) cells and their interactions with cancer cells over time. The goal is to learn whi…
Matched conditions: MYELODYSPLASTIC SYNDROME
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC