MYELODYSPLASTIC SYNDROME
Clinical trials for MYELODYSPLASTIC SYNDROME explained in plain language.
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Blood cancer transplant study tests two conditioning regimens
Disease control TerminatedThis study looked at adults with certain blood cancers (like leukemia) who were getting a stem cell transplant. It compared two different chemotherapy combinations given before the transplant to see which one better prevented the cancer from coming back within a year. The study w…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE3 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated May 26, 2026 07:12 UTC
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Promising combo for tough blood cancer hits roadblock
Disease control TerminatedThis study looked at combining two drugs, venetoclax and azacitidine, to treat people with a serious type of bone marrow cancer called high-risk myelodysplastic syndrome (MDS). The goal was to find the safest dose and see if the combination could shrink or control the cancer. The…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 07:08 UTC
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Blood cancer transplant study tests safer drug combo to prevent deadly complication
Disease control TerminatedThis study looked at people with blood cancers receiving a stem cell transplant from an unrelated donor. The goal was to find which of two drug combinations (cyclosporine and sirolimus with either MMF or post-transplant cyclophosphamide) better prevents a serious side effect call…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 07:08 UTC
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Experimental combo targets hard-to-treat blood cancers
Disease control TerminatedThis early-stage study tested two drugs, AZD1775 and belinostat, in 20 adults with certain blood cancers (like acute myeloid leukemia) that came back or didn't respond to prior therapy. The main goal was to find the safest dose and check side effects. The study was stopped early,…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 18, 2026 12:10 UTC
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Promising combo for tough leukemias hits roadblock: trial ends early
Disease control TerminatedThis study tested a combination of two drugs, venetoclax and decitabine, in 235 people with certain blood cancers (like acute myeloid leukemia and high-risk myelodysplastic syndrome) that either came back or didn't respond to prior treatment, or in older adults who couldn't handl…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 18, 2026 12:00 UTC
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Experimental combo for tough leukemia shows promise but study halted early
Disease control TerminatedThis study tested a chemotherapy combination containing cladribine for people whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had returned or not responded to prior treatment. The goal was to see if the treatment could wipe out signs of the disease …
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 06, 2026 16:01 UTC