HEALTHY ADULTS

This study tested a home-use dual-light antibacterial device to see if it could remove more dental plaque than regular brushing and flossing alone. Twenty healthy adults took part in a crossover trial where they used the device alongside their normal routine. The goal was to meas…

This study looked at how an inhaled medication called treprostinil affects exercise ability in people with pulmonary hypertension caused by interstitial lung disease. 29 participants took the drug for 3 months. Researchers measured heart function and breathing efficiency during e…

This study tested whether daily omega-3 supplements (fish oil) can reduce stress, anxiety, and depression while improving memory and sleep in 64 Saudi adults who were feeling highly stressed. Participants took either omega-3 capsules or a placebo for three months. Results showed …

This study looked at whether a chicken extract supplement can improve mental energy—things like focus, motivation, and tiredness—in 189 healthy adults aged 35 to 64. Participants took either the extract or a placebo, and researchers measured their reaction time, attention, mood, …

This study looked at how the drug carbamazepine changes the way the body handles another medicine called PF-07220060. Fourteen healthy adults took PF-07220060 alone and then again after taking carbamazepine for several days. Blood samples were collected to measure drug levels, he…

This study looked at how different levels of liver damage affect the way the body handles a single dose of the experimental drug KP-001. Twenty-four adults with either healthy livers or mild to moderate liver problems took part. Researchers measured drug levels in the blood to se…

This study looked at how two common drugs (itraconazole and probenecid) change the way a new medicine, PF-07220060, moves through the body. Twenty-five healthy adults took the new medicine alone and then with the other drugs. The goal was to see if the other drugs affect the leve…

This study looked for chemicals in blood and urine that can tell researchers what foods people have eaten, like beef, beans, and eggs. Thirty healthy adults ate controlled meals and gave samples over several days. The goal is to replace unreliable food diaries with objective lab …

This study looked at how four different versions of Urolithin A (Mitopure) are absorbed and processed in the body. Forty-eight healthy adults aged 18 to 45 took a single dose of one formulation. Researchers measured levels of Urolithin A in the blood over time and tracked any sid…

This study looked at how healthy men process the experimental drug PF-07104091. Nine participants took the drug by mouth and later received a tiny radioactive dose to track where it goes. The goal was to measure how much drug enters the blood and how it leaves the body through ur…

This study aimed to find chemicals in blood and urine that show what people have eaten, instead of relying on what they say they ate. 32 healthy adults ate controlled diets and gave samples. The goal is to create more accurate ways to measure diet in future research.

This study looked at whether a special video game that combines physical exercise with cognitive challenges can improve attention and working memory in healthy adults. 49 participants were assigned to different training groups over 8 weeks. The goal was to understand if combining…

This study looked at how carbamazepine, a drug that can change how the body processes other medications, affects the processing of PF-07248144. Twelve healthy adults took PF-07248144 alone and then with carbamazepine. Researchers measured drug levels in the blood to understand th…

This study followed over 5,000 adults aged 55-70 in Germany for 8 years to learn how retirement, loneliness, and physical activity change as people age. Researchers surveyed participants three times between 2013 and 2019. The goal was to better understand the aging process, not t…

This study looked at how one session of aerobic exercise at different intensities affects brain blood flow, stress markers, and memory in healthy adults and those with mild stress. 24 people participated, and researchers measured changes in the brain and blood. The goal was to un…

This study tested two different pill versions of an experimental drug (PF-07248144) in 24 healthy adults. The goal was to see how well each version is absorbed by the body, not to treat any disease. Participants received a single dose of each pill at different times, and research…

This completed Phase 1 study looked at how two common medicines—cyclosporine (an immunosuppressant) and clarithromycin (an antibiotic)—change the levels of a new drug called PF-07328948 in the body. Twenty-six healthy adults took the new drug alone and then with each other medici…

This early-stage study looked at whether a new drug called CHI-554 is safe to take with alcohol. 29 healthy adults took part in a double-blind trial where some received the drug and some a placebo, then both groups had alcohol. Researchers monitored side effects, liver function, …

This study looked at how bismuth subsalicylate (the active ingredient in Pepto-Bismol) affects the bacteria living in the gut. 34 healthy adults took the medicine for 2 days, and researchers compared their stool samples before and after. The goal was to understand if this common …