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Anti-Aging gene therapy trial launches in healthy volunteers

NCT ID NCT07285629

First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 27 times

Summary

This early-phase study tests a gene therapy that delivers two proteins, klotho and follistatin, via injection into healthy adults aged 50 to 80. The goal is to see if it safely raises these protein levels and improves health or cognition. Thirty participants will be monitored for side effects and changes in quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Apeiron Center

    RECRUITING

    Austin, Texas, 78701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Global Alliance of Regenerative Medicine (GARM) Clinic

    NOT_YET_RECRUITING

    Roatán, Bay Islands, Honduras

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

klotho and follistatin gene therapy (nonviral plasmid injection)

What this could lead to

If successful, this could point toward a gene therapy that slows aging or improves cognitive function in older adults.

What could go wrong

This is a very early, small pilot study with only 30 healthy volunteers. It may not show clear benefits, and safety risks from gene therapy are still unknown.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.