HEALTHY ADULTS

This study tests two experimental COVID-19 booster vaccines alongside two already-approved ones in 48 healthy adults aged 18 to 65. Participants receive one injection and are monitored for side effects and antibody levels over 48 weeks. The goal is to see if the new vaccines are …

This study tests an experimental mRNA-based flu vaccine in healthy adults aged 18 and older. Researchers want to see if it is safe and can trigger a strong immune response against the flu. About 770 participants will receive one dose of either the experimental vaccine or an appro…

This early-phase study tests a gene therapy that delivers two proteins, klotho and follistatin, via injection into healthy adults aged 50 to 80. The goal is to see if it safely raises these protein levels and improves health or cognition. Thirty participants will be monitored for…

This study tests whether taking probiotics before and during a short trip abroad can prevent stomach issues like traveler's diarrhea and sleep problems. 46 healthy adults will be randomly assigned to take either a probiotic or a placebo. The goal is to see if probiotics help main…

This early-stage study tests a new gene therapy that aims to increase levels of a protein called Klotho, which is linked to better brain function and overall health. The trial involves 24 healthy adult volunteers who will receive a single injection of the therapy. Researchers wil…

This study tests whether adding electrical stimulation or special sound beats to mirror therapy can improve leg function in people who had a stroke at least 6 months ago. Researchers will measure muscle strength, spasticity, and brain activity in 72 adults aged 20-80. The goal is…

This study tests whether two passive warm-up methods—infrared heating and therapeutic massage—can improve balance and jump performance in healthy adults aged 18-35. One hundred participants will be randomly assigned to receive either infrared or massage after a short cycling warm…

This study in Lahore, Pakistan, compares identical and fraternal twins to understand how genetics and environment influence diet results. Over 12 weeks, 60 healthy twins will follow a balanced diet, and researchers will measure changes in body fat and blood sugar. The goal is to …

This study looks at how the experimental drug PF-08049820 is absorbed in healthy adults. It tests three different forms of the drug, taken with or without food, and also with another drug that reduces stomach acid. The goal is to understand the best way to give the drug in future…

This study looks at how eating different amounts of fiber changes the compounds in your breath. Healthy adults aged 18-65 will eat either a low-fiber or high-fiber diet for three days, and researchers will measure breath and gut samples. The goal is to understand how gut bacteria…

This study looks at whether eating pecans every day for 3 months can improve blood fats, blood pressure, thinking skills, and gut bacteria in healthy adults aged 45 to 75. Participants will eat pecans during one period and avoid them during another, with blood and stool samples c…

This early-stage study tests the safety of a new drug called GS3-007a in 32 healthy Chinese adults aged 18-45. Participants receive either the drug or a placebo, and researchers monitor side effects and how the drug moves through the body. The study also checks if food affects dr…

This study tests which method is more accurate for placing dental implants: a custom-made guide or a dynamic navigation system that shows the dentist where to drill on a screen. Twenty healthy adults with at least one missing upper tooth will take part. The goal is to see which a…

This study looks at how people with mild multiple sclerosis adjust their walking when faced with obstacles or sudden changes, compared to healthy adults. Researchers will use motion sensors and brain activity monitors to measure these skills. The goal is to find better ways to de…

This study looks at how adults aged 18 to 65 move their eyes and body when using digital devices with different eyeglasses. Researchers will track eye and head movements during simple screen tasks. The goal is to understand how age and glasses type affect posture and gaze. No tre…

This study looks at whether strengthening your breathing muscles and taking a nitrate supplement (like the stuff in beets) can help healthy adults exercise longer in conditions that mimic high altitude. Researchers will measure how long 80 volunteers, aged 18 to 40, can cycle bef…

This early-stage study is testing a new drug called EDG-15400 in 108 healthy adults to see if it is safe and how the body handles it. Participants will receive either the drug or a placebo as a single dose or multiple doses. The goal is to gather safety information, not to treat …

This early-stage study tests a new drug called MIB-725 in 32 healthy adults aged 19 to 60. Participants receive a single dose (100 to 800 mg) and are monitored for side effects and how the drug moves through the body. The goal is to see if the drug is safe before testing it in pe…

This study tests whether 5 weeks of special breathing exercises can reduce breathlessness and improve exercise performance in healthy cyclists and triathletes. Researchers will measure breathing discomfort and oxygen use during exercise. The goal is to learn how to personalize br…