HEALTHY ADULTS

This study tested a new home-use device that uses two types of light to kill bacteria on teeth. 20 healthy adults used the device along with regular brushing and flossing to see if it removed more plaque than cleaning alone. The goal was to improve daily dental care.

This study looked at whether a special video game that combines mental challenges with physical activity can improve attention and working memory in healthy adults. 49 participants were assigned to different training groups and tested over 8 weeks. The goal was to understand if c…

This study looked at how healthy men process the experimental drug PF-07104091. Nine participants took the drug by mouth and later received a tiny radioactive tracer to track where the drug goes and how it leaves the body. The goal was to measure absorption, breakdown, and elimin…

This study tested a new medicine called PF-07940369 in 30 healthy adults to see if it is safe and how the body handles it. Participants took the drug or a placebo by mouth for 14 days while staying at a clinic. The study is complete and will help decide if further testing is poss…

This study looked at how bismuth subsalicylate (the active ingredient in Pepto-Bismol) changes the bacteria in the gut. 34 healthy adults took the medicine for 2 days and provided stool samples over several weeks. The goal was to understand how this common over-the-counter drug a…

This study looked at how two common drugs (itraconazole and probenecid) change the way a new experimental medicine (PF-07220060) behaves in the body. It involved 25 healthy adults who took the new medicine alone and then again with the other drugs. The goal was to gather safety a…

This study tested whether blood and urine samples can accurately show what healthy people ate, instead of relying on food diaries. Thirty-two healthy adults ate carefully controlled meals, and researchers measured chemicals in their blood and urine to find reliable diet markers. …

This study looked at how one session of aerobic exercise at different intensities affects stress markers, brain blood flow, and thinking skills in 24 healthy adults and those with mild stress symptoms. Researchers measured changes in the brain's prefrontal cortex and blood sample…

This early-stage study tested whether a new drug called CHI-554 is safe when taken with alcohol. 29 healthy adults participated in a double-blind trial where some received the drug and others a placebo. Researchers monitored side effects, liver function, and blood alcohol levels …

This study looked at how the drug carbamazepine changes the way the body handles another drug called PF-07220060. Fourteen healthy adults took part in two periods: first, they took a single dose of PF-07220060 alone, then later they took carbamazepine for several days before anot…