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Twins on a diet: can genes predict weight loss success?

NCT ID NCT07362550

Knowledge-focused Sponsor: University of Veterinary and Animal Sciences, Lahore - Pakistan Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study in Lahore, Pakistan, is recruiting 60 healthy twins to see how genetics and environment influence the effects of a balanced diet. Over 12 weeks, both identical and fraternal twins will follow a WHO-aligned diet. Researchers will measure changes in body fat, blood sugar, and cholesterol to understand why some people respond better to diet changes than others.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Balanced diet (whole grains, lean proteins, healthy fats, fruits, vegetables)
What this could lead to
If successful, this could help create personalized nutrition plans based on genetics, improving health in Pakistan.
What could go wrong
This is a small, early-stage study with only 60 participants. Results may not apply to everyone, and diet adherence can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female twins aged 18-60 years. * Confirmed zygosity (MZ or DZ) based on a validated twin zygosity questionnaire. * Both twins willing to participate for the entire intervention period. * Free from chronic diseases requiring specialized diets (e.g., type 1 diabetes, celiac disease). * Not currently enrolled in another dietary or lifestyle intervention study. Exclusion Criteria: * Pregnant or lactating women. * Use of lipid-lowering, glucose-lowering, or weight-loss medications in the past 3 months. * Major gastrointestinal disorders or conditions affecting nutrient absorption. * Unwillingness to follow individualized dietary counseling or complete study assessments.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy adults

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Veterinary and Animal Sciences, Lhr.

    RECRUITING

    Lahore, Punjab Province, 54000, Pakistan

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