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Can a quick bike ride beat stress? study tests best exercise intensity

NCT ID NCT06245538

Knowledge-focused Sponsor: The Swedish School of Sport and Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how a single session of cycling at moderate or vigorous intensity affects stress markers, inflammation, and brain activity in 24 healthy adults and those with mild stress symptoms. Participants did 20 minutes of seated rest, moderate cycling, or vigorous cycling on separate days. Researchers measured changes in brain blood flow, stress-related blood biomarkers, and working memory performance. The goal is to understand which exercise intensity offers the best short-term benefits for stress and brain health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
physical exercise (cycling at moderate or vigorous intensity)
What this could lead to
If successful, this could help identify the best exercise intensity for reducing stress and improving brain function in people with mild stress symptoms.
What could go wrong
This is a small, completed study with only 24 participants, so results may not apply to everyone. It looks at short-term effects, not long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Feb 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants experiencing sub-clinical levels of stress-related symptoms: * Age: 20-40 years * Absence of contraindications to physical exercise * Do not participate in any other study * Total score on the self-assessment scale 4-factor Shirom-Melamed Burnout Measure-19 lower than or equal to 4.00 Exclusion Criteria: * Medical contraindication to catheterization of the antecubital vein and blood sampling * Dementia * Alcohol abuse * Smoking * Chronic medication that is considered to affect study outcomes * Chronic disease/syndrome such as migraine, fibromyalgia, chronic fatigue syndrome, bipolar syndrome, high blood pressure, cardiovascular disease, chronic obstructive pulmonary disease (COPD) or other lung disease * Post-COVID * Other somatic diseases, disorders, or injuries that may affect the physical ability during physical exercise

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Conditions

The condition(s) this trial relates to.

Neuroinflammatory Diseases Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adults with stress-related symptoms Healthy adults

Contacts and locations

Locations

  • The Swedish School of Sport and Health Sciences

    Stockholm, 11433, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.