DEPRESSIVE DISORDER

This study tested a special therapy (OPT-A) for teens aged 10-17 who have both substance use problems and mood or anxiety disorders. 140 teens took part and were followed for 18 months. The goal was to see if the therapy could reduce drug use and improve mental health better than…

This study tested a program called iDOVE2 for teens at risk of peer violence and depression. It combined a short session in the emergency department with automated text messages to help prevent these issues. The study involved 620 teens and measured changes in violent behavior an…

This study tested a 6-week school program designed to prevent anxiety and depression in American Indian children. 28 children in grades 3-6 from a tribal reservation took part. The program was adapted to include local culture and traditions. Researchers measured changes in anxiet…

This study looked at whether a daily probiotic drink (like Yakult) can reduce cold symptoms in triathletes, who often get sick after intense training and competition. 80 healthy adult triathletes drank either the probiotic or a placebo for weeks before and after a race. Researche…

This study tested a non-invasive brain stimulation technique called HD-tDCS to see if it could reduce physical symptoms (like aches and fatigue) in people with depression. 57 adults with depression received either real or fake stimulation over several sessions. Researchers used M…

This study tested whether taking part in art activities, like painting or music, can improve mental wellbeing and reduce symptoms of anxiety and depression. 382 people with various mental health issues were randomly assigned to either an art program or a waiting list. The results…

This study tested a gentle, non-invasive brain stimulation technique called HD-tACS in 60 adults with depression and suicidal thoughts. The goal was to see if it could reduce the severity of those thoughts and understand how it changes brain activity. Participants received the st…

This study tested whether a program called PRISM (Promoting Resilience in Stress Management) is practical and helpful for young adults aged 18-39 who have been diagnosed with cancer or desmoid tumors. The program aims to reduce symptoms of depression and anxiety. Researchers enro…

This pilot study tested a 10-session behavioral activation program delivered via teletherapy to help adults with moderate-to-severe depression increase physical activity and reduce depressive symptoms. Sixty-five participants used a smartphone and Fitbit to track activity. The st…

This study tested if unlimited text-based therapy works better than once-a-week therapy for depression. Over 1,100 adults with depression took part. Researchers also looked at the best next steps for people who didn't improve with either option. The goal is to create a flexible, …

This study tested whether a mobile app could help reduce anxiety and depression in 63 adults who were already receiving medication for opioid use disorder. Participants used the digital program for four weeks alongside their usual care. The goal was to see if the app was easy to …

This study looked at whether a mix of online and in-person therapy works as well as standard face-to-face therapy for adults with major depression. 105 French adults took part. The goal was to see if the blended approach could ease symptoms and be more cost-effective.

This study tested whether an optimized multichannel tDCS (a gentle brain stimulation technique) works better than standard tDCS or a fake treatment for easing depression. Sixty adults with moderate-to-severe major depression received one of the three approaches. The goal was to s…

This study tested a short, practical program called Problem Management Plus (PM+) to help adults with depression or anxiety in a primary care clinic in Chile. 56 participants were randomly assigned to either PM+ or their usual care. The goal was to see if PM+ was feasible and acc…

This study tested an online cognitive-behavioral therapy (CBT) program for 60 teenagers with anxiety and depression. The program, called AMTE, teaches skills to manage emotions and reduce symptoms. Results showed that the online therapy was more effective than a control group in …

This study tested a new, non-invasive light therapy called transcranial photobiomodulation (tPBM) for people with major depression. 50 adults received either active light or a sham treatment on their forehead three times a week for six weeks. The goal was to see if this light the…

This study tested whether using a person's DNA to choose an antidepressant works better than standard care for cancer patients with depression or anxiety. About 99 adults with cancer took part. Researchers compared changes in mood and quality of life between those who got DNA-gui…

This study tested a group version of a therapy program for 31 adolescents with mild to moderate anxiety or depression in Spanish public mental health clinics. The program aimed to reduce symptoms and improve daily functioning. Researchers checked progress right after treatment an…

This study tested a group version of a therapy program for 15 teenagers with severe anxiety or depression in a Spanish day hospital. The program aimed to help teens manage their emotions and reduce symptoms. Researchers checked how teens felt before, right after, and 3, 6, and 12…

This study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…

This study tested a new artificial intelligence tool called CBTpro that helps therapists improve their skills in cognitive behavioral therapy for people with psychosis. Over 600 adults with conditions like schizophrenia or bipolar disorder took part. The goal was to see if the to…

This study looked at a temporary side effect called dissociation—feeling disconnected from your thoughts, body, or surroundings—that can happen when taking esketamine for depression. Researchers interviewed 15 people who had this experience to better understand what it feels like…

This study tested whether an Instagram channel called 'ich bin alles' could help teenagers learn more about depression, feel less ashamed, and be more willing to get help. About 170 teens who already use Instagram took part. The goal was to see if social media can be a friendly, …

This study followed 1290 adults with type 1 or type 2 diabetes for two years to see how mental health issues like depression, anxiety, and eating problems relate to blood sugar control. Participants completed surveys, interviews, and daily smartphone check-ins about mood and stre…

This study tested whether alerting police officers that a person has a serious mental illness during a routine check can reduce arrests and help them stay in treatment. About 1,400 adults with conditions like schizophrenia, bipolar disorder, or major depression who had been arres…

This study examined blood samples from 300 people to see if depression is linked to faster cell aging. Researchers measured telomere length and stress levels in white blood cells. The goal was to find genetic markers that could help doctors better understand the severity and phys…

This study looked at how young people feel about depression education shared on Instagram. Researchers showed 18 teens (some with depression, some without) posts from the 'ich bin alles' channel and asked what they thought. The goal was to understand if social media can be a help…