CROHN'S DISEASE

This study is testing whether risankizumab injections can help control symptoms and reduce intestinal inflammation in adults with moderate to severe Crohn's disease. Participants will receive either the study drug or a placebo injection for up to 24 weeks, followed by an extended…

This study is testing an injectable medication called guselkumab for adults with moderate to severe Crohn's disease. It aims to see if the drug can reduce symptoms like abdominal pain and diarrhea, and improve gut inflammation seen on a scope. Over 1,400 participants will receive…

This study is testing how well the drug mirikizumab works and how safe it is for people with Crohn's disease over a long period. It follows nearly 1,000 participants who completed earlier studies of the same medication. The main goals are to see if the drug reduces intestinal inf…

This early-stage study aimed to test the safety of injecting donor stem cells directly into fistulas (abnormal tunnels) in people with Crohn's disease. The goal was to see if these injections could help the fistulas close and heal. The study was withdrawn before any participants …

This early-stage study is testing the safety and tolerability of an oral herbal formula called E-B-FAHF-2 in adults with mild-to-moderate Crohn's disease. The goal is to see if this concentrated plant-based medicine can safely help maintain remission, filling a gap where few appr…

This study is observing patients with moderate to severe Crohn's disease who are already being treated with the drug Entyvio (vedolizumab) in their regular doctor's care. The main goal is to collect long-term information on the drug's safety and how well it works to control the d…

This study is testing whether combining two existing drugs, guselkumab and golimumab, is better at controlling Crohn's disease than using either drug alone. It involves about 700 adults with moderate to severe Crohn's disease. The main goal is to see if the combination leads to f…

This study is testing whether two special diets can help people with active Crohn's disease or ulcerative colitis. Forty adults will follow either a partial liquid elemental diet or a specific carbohydrate diet for six weeks. Researchers will check if the diets reduce gut inflamm…

This study is collecting long-term health information from nearly 5,000 children and teenagers with Crohn's disease, ulcerative colitis, or other inflammatory bowel diseases. Researchers will follow participants for up to 20 years to understand the safety of treatments and how th…

This study is creating a large, long-term registry of patients with Crohn's disease or ulcerative colitis to learn how these conditions behave and how treatments perform in everyday clinic settings. It will follow 15,000 adults and children (age 2+) for five years, collecting inf…

This study is collecting information about how Brazilian patients with Crohn's disease or ulcerative colitis use the medication vedolizumab. Researchers are reviewing existing treatment records from about 1006 patients to understand how long they stay on treatment and what outcom…

This study is observing how a new online tool, called CDPATH™, is used in regular doctor's offices. The tool estimates an adult patient's risk of developing Crohn's disease complications within the next three years. Researchers are enrolling about 200 recently diagnosed patients …