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Can a monthly infusion tame stubborn IBD? new study tests faster dosing

NCT ID NCT04738942

First seen Jun 17, 2026 · Last updated Jun 17, 2026

Summary

This study tests whether giving vedolizumab every 4 weeks instead of every 8 weeks can help Japanese patients with moderate to severe ulcerative colitis or Crohn's disease whose symptoms returned during standard treatment. About 56 participants will receive the drug intravenously every 4 weeks, and doctors will check for symptom improvement after 12 weeks. The goal is to see if a more frequent dose can regain control of the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fukuoka University Chikushi Hospital

    Chikushino-shi, Fukuoka, Japan

  • Hirosaki University Hospital

    Hirosaki, Aomori, Japan

  • Hyogo College of Medicine Hospital

    Nishinomiya, Hyōgo, Japan

  • Ieda Hospital

    Toyota, Aichi-ken, Japan

  • Infusion Clinic.

    Osaka, Japan

  • Institute of Science Tokyo Hospital

    Bunkyo-ku, Tokyo, Japan

  • Jichi Medical University Hospital

    Shimotsuke, Tochigi, Japan

  • Juntendo University Hospital

    Bunkyo-ku, Tokyo, Japan

  • Keio University Hospital

    Shinjuku-ku, Tokyo, Japan

  • Kitasato University Hospital

    Sagamihara, Kanagawa, Japan

  • Kitasato University Kitasato Institute Hospital

    Minato-ku, Tokyo, Japan

  • Kyorin University Hospital

    Mitaka, Tokyo, Japan

  • Ofuna Chuo Hospital

    Kamakura, Kanagawa, Japan

  • Osaka Metropolitan University Hospital

    Osaka, Japan

  • Sapporo Kosei General Hospital

    Sapporo, Hokkaido, Japan

  • Toho University Sakura Medical Center

    Sakura, Chiba, Japan

  • Tohoku University Hospital

    Sendai, Miyagi, Japan

  • Tokyo Yamate Medical Center

    Shinjuku-ku, Tokyo, Japan

  • Tsujinaka Hospital

    Kashiwa, Chiba, Japan

  • Yokohama City University Medical Center

    Yokohama, Kanagawa, Japan

Conditions

The condition(s) this trial relates to.

Crohn disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.