CORONARY DISEASE

This study is watching 1,000 adults who get a DESyne X2 stent to open blocked heart arteries. Researchers track deaths, heart attacks, and repeat procedures for up to a year. The goal is to see how safe and effective the stent is in routine hospital care.

This study tests whether using just one blood thinner (single antiplatelet therapy) is safer and as effective as two blood thinners (dual antiplatelet therapy) in older adults or those at high risk of bleeding who have had a heart procedure with a drug-coated balloon. About 576 p…

This study is checking how well two new stents (Synergy XD and Synergy Megatron) work in everyday medical practice for people with coronary artery disease. About 2000 adults getting these stents will be followed to see if they have fewer heart attacks, need repeat procedures, or …

This study tests whether repeating a simple arm-cuff procedure (remote ischemic preconditioning) over several months can improve blood flow to the heart muscle in 210 people who have had coronary artery bypass surgery. The goal is to see if this safe, non-drug approach helps the …

This study tests whether using a special device (orbital atherectomy) to grind down calcium deposits before placing a stent is better than the standard balloon method. About 200 adults with hardened heart arteries will be randomly assigned to one of the two approaches. The goal i…

This study looks at 600 people who had a major heart attack and have other blockages that are not severe enough to need immediate treatment. Some of these blockages are unstable and could cause another heart attack. The trial compares two approaches: placing stents in these unsta…

This study compares two non-invasive tests for coronary heart disease: a CT scan of the heart arteries versus a heart ultrasound combined with a neck artery ultrasound. The goal is to see which approach better detects both minor and severe blockages, helping doctors choose the ri…

This study aims to understand how coronary artery disease progresses in young adults aged 18 to 45. Researchers will enroll 10,000 participants who have had a coronary CT scan and follow them over several years with repeat scans. By analyzing health data, lifestyle, and genetics,…

This study tests new, lower-radiation CT scan methods for taking pictures of the heart and blood vessels. Researchers want to see if these new techniques are accurate and can help predict future heart problems like heart attacks or strokes. Up to 5,000 adults who need a heart CT …

This study looks at a new method to check blood flow in heart arteries after treatment in patients with blockages in multiple vessels. The new method uses a special wire and a drug (nitroglycerin) instead of the standard drug adenosine, which can cause side effects. Researchers w…