CORONARY DISEASE

This study compared two ways to treat people with multiple blocked heart arteries: a less invasive procedure using stents guided by a special pressure wire (FFR-guided PCI) versus open-heart bypass surgery (CABG). About 1,500 adults with three blocked vessels took part. The goal …

This study tested a very small balloon catheter (0.85-1.25 mm) in 170 people with completely blocked heart arteries (chronic total occlusion). The balloon was used to open the blockage before placing a stent. Researchers checked if the balloon could be safely delivered, inflated,…

This study looked at whether taking two blood thinners (clopidogrel and aspirin) for a longer time after getting a heart stent helps prevent future heart attacks, strokes, or death in people with multiple blocked heart arteries. About 8,250 adults aged 18-75 who already had a ste…

This study tested two methods of pacing the left side of the heart in people with severe heart failure. The standard method paces from outside the heart, while the new method paces from inside. The goal was to see if the new method improves heart function more and helps more pati…

This study aimed to find out if silent myocardial ischemia—a condition where the heart doesn't get enough blood without causing chest pain—raises the risk of heart-related death or problems in people with coronary heart disease. Researchers followed patients for one to three year…

This study collected information from 66 adults who had a heart CT scan to measure the amount of radiation used in everyday medical practice. The goal was to see how radiation doses vary between different hospitals and CT machines, and how often dose-saving techniques are used. T…

This study looked at the gut bacteria and bile acids of 80 people—some with coronary artery disease and some healthy. The goal was to see if differences in gut microbes and bile acids are linked to heart disease. No treatment was given; it was purely observational.