CONSTIPATION

This study compared two surgical techniques (circular Soave and heart-shaped anastomosis) in 177 children under 14 with Hirschsprung's disease. The goal was to see which method leads to better bowel control and fewer complications like soiling or constipation. Results help guide …

This study looked at 20 children with Hirschsprung disease, a condition where part of the bowel lacks nerve cells, causing severe constipation. Researchers compared two surgical methods—Swenson and Soave—to see which one works better. The main focus was on how long the surgery ta…

This study tested a drug called isatuximab in 43 people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. The drug is a lab-made antibody that helps the immune system attack the faulty cells making these proteins. The goal was to see if it could lowe…

This study tested a low-volume irrigation device (Qufora IrriSedo MiniGo) in 92 adults with fecal incontinence, chronic constipation, or both. The goal was to see if it improved bowel function and daily life. Participants used the device at home and reported their symptoms.

This study tested a special insole designed to relieve constipation in people receiving palliative care. 139 participants either walked with the insole or without it for 20 minutes daily over four weeks. The goal was to see if the insole, based on reflexology, could improve bowel…

This study tested whether two different probiotic supplements could improve constipation and weight gain in 30 children with cerebral palsy. Participants took either a probiotic or a prebiotic-enriched supplement daily for 28 days. Caregivers tracked bowel movements and stool con…

This study looked at whether one session of abdominal massage can improve blood vessel stiffness, muscle oxygen levels, and exercise ability in adults with chronic constipation. About 30 people took part, with some receiving the massage and others resting instead. Researchers mea…

This study looked at whether giving people a gentle abdominal massage before surgery could help prevent constipation after the operation. Sixty adults who were already constipated and scheduled for general surgery took part. Half received the massage, and the other half did not, …

This study tested a treatment called posterior tibial nerve stimulation (PTNS) for children ages 8-18 with constipation caused by pelvic floor dyssynergia. Researchers compared real PTNS to a sham (fake) treatment in 40 children to see if it improves bowel function. The goal was …

This study looked at whether a gentle abdominal massage can help with constipation in people receiving hemodialysis. 49 adults took part. Researchers measured changes in constipation severity, quality of life, and stool consistency. The goal was to see if this simple, drug-free a…

This study looked at whether ear massage can help prevent or reduce constipation in people who had leg surgery. Constipation is a common problem after such surgeries. The researchers tested ear massage on 40 patients to see if it could help bowel movements return sooner. The goal…

This study tested whether a probiotic called Weizmannia coagulans BC99 can help relieve chronic constipation in adults. 90 Chinese adults with constipation took either the probiotic or a placebo for a period of time. The goal was to see if the probiotic improved bowel movement fr…

This study tested a device called MOWOOT for adults with chronic constipation. It compared the device to standard care (trans-anal irrigation). The goal was to see if the device improves quality of life and constipation symptoms. 86 adults took part in the study.

This study looked at whether taking a laxative (polyethylene glycol 3350) before surgery, in addition to after surgery, reduces discomfort with bowel movements compared to taking it only after surgery. It involved 74 women undergoing minimally invasive surgery for pelvic organ pr…

This study tested whether applying a magnetic field to the belly can reduce constipation severity in people with long-term constipation. 75 adults were split into three groups: one received real magnetic therapy twice a week for 8 weeks, one received a fake (sham) treatment, and …

This study tested whether a telerehabilitation-based exercise program could reduce constipation symptoms and improve quality of life in adults. 32 participants with constipation took part. The approach combined exercise and education delivered remotely, aiming to offer a convenie…

This study looked at whether treating constipation in people with chronic kidney disease (CKD) is practical and might improve health. Fourteen adults with both CKD and constipation received treatment. The main goal was to see if patients would follow the treatment and provide sam…

This study tested a new, faster care pathway for people with chronic constipation at a gastroenterology clinic. Researchers wanted to see how often patients received recommended tests and pelvic floor therapy, and how satisfied they were with their care. 109 adults with chronic c…

This early-phase study tested how two drugs, neostigmine and glycopyrrolate, move into the bloodstream when given through a skin patch (iontophoresis) compared to an IV. Six healthy adults took part to help researchers understand the drugs' behavior. The goal was to gather data f…

This study looked at 236 people, including those with chronic constipation or fecal incontinence and healthy volunteers, to better understand how the rectum and anus work. Researchers tested a new device called Fecobionics that combines several tests into one, aiming to make diag…

This early-stage study tested whether a small, wireless patch could safely deliver two bowel medications (neostigmine and glycopyrrolate) through the skin using a tiny, unnoticeable electric current. Only 2 able-bodied volunteers took part to check safety and how the drugs enter …