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Probiotics show promise for constipation in kids with cerebral palsy

NCT ID NCT07393256

Symptom relief Sponsor: Ordu University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether daily probiotic supplements could improve constipation and weight gain in 30 children with cerebral palsy. Participants took either Lactobacillus reuteri or a prebiotic-enriched Lactobacillus rhamnosus for 28 days. Caregivers tracked bowel movements and stool consistency using a diary. The goal was to see if these supplements are safe and effective for easing constipation and supporting better nutrition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Nov 2022

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 months to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 6 months and 18 years * Clinical diagnosis of cerebral palsy * Gross Motor Function Classification System (GMFCS) levels III, IV, or V * Chronic constipation diagnosed according to Rome IV criteria * Stable medical condition * Ability to receive oral or enteral nutrition Exclusion Criteria: * Cerebral palsy due to degenerative neurological disorders * Constipation due to a known organic cause * Congenital gastrointestinal tract malformations * Inflammatory bowel disease * Metabolic diseases * History of kidney failure * Use of antibiotics, probiotics, or prebiotics within one month prior to enrollment * Anticipated poor adherence to the study protocol * Requirement for hospitalization during the study period

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Conditions

The condition(s) this trial relates to.

cerebral palsy constipation disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy (CP) Constipation Probiotic

Contacts and locations

Locations

  • Ordu University Faculty of Medicine, Department Of Pediatric Surgery

    Ordu, Outside of the US, 52200, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.