CONSTIPATION

This study is testing a new, more detailed diagnostic tool called high-resolution manometry to better understand severe constipation that doesn't respond to standard laxatives. Researchers will compare measurements from patients with this severe condition to those from healthy vo…

This study aims to improve a treatment called biofeedback for adults with chronic constipation caused by a specific muscle coordination problem. Researchers will measure how well biofeedback helps people empty their bowels more easily and reduces their symptoms. The goal is to ma…

This study is testing whether drinking a probiotic milk beverage daily for four weeks can help relieve constipation symptoms in Filipino adults. Researchers want to see if it improves stool consistency, how often people go, how long it takes, and reduces stomach discomfort. They …

This study is testing whether a daily probiotic supplement can improve gut health and ease constipation in healthy, active adults. About 30 participants will take the probiotic and a placebo for separate 4-week periods to compare the effects. Researchers will use questionnaires t…

This study is testing whether a drug already approved for irritable bowel syndrome can help relieve constipation in people with cystic fibrosis. About 25 participants will take the medication twice daily for four weeks. They will track their bowel movements and symptoms using dai…

This study is testing whether a specific probiotic supplement can safely help improve bowel movements in adults with chronic constipation. Researchers will compare the probiotic against a placebo (a dummy pill) in 80 participants. The main goal is to see if the probiotic helps sh…

This study is testing which of two common laxative methods works better to prevent painful constipation after pelvic organ prolapse surgery. Researchers will compare an oral medication (senna) with a rectal suppository (bisacodyl) in 88 women having this type of vaginal surgery. …

This small pilot study is testing whether a specific liquid probiotic drink can improve constipation symptoms and quality of life. It will involve 20 adults who self-report constipation. Researchers will track changes in bowel habits, symptoms, and gut transit time using question…

This study is testing whether a popular over-the-counter dietary supplement called Inno Cleanse can reduce feelings of bloating in otherwise healthy adults. Researchers will give the supplement or a placebo to 30 participants for two weeks to see if it helps. They will also check…

This study is testing whether an herbal formula called Ma-Zi-Ren-Wan (MZRW) can help relieve constipation in people who have survived cancer. Researchers will compare MZRW to a placebo (a dummy pill) over two weeks to see if it increases comfortable bowel movements. They will als…

This study is testing whether a medication called pyridostigmine can safely and effectively treat chronic constipation in people with Parkinson's disease. Sixteen participants with Parkinson's and significant constipation will take the medication for several weeks while tracking …

This study is testing a new device called Fecobionics to better understand a common cause of constipation called pelvic floor dyssynergia. Researchers will use the small, balloon-like device to measure pressures and movements in the rectum and anus of 24 participants before and d…