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Could probiotics be the key to better digestion?

NCT ID NCT07765004

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 14, 2026 · Last updated Aug 18, 2026 · Updated 2 times

Summary

This trial tests whether taking a daily probiotic supplement for 8 weeks can relieve constipation in adults. Participants are randomly assigned to receive either the probiotic or a placebo, and researchers track changes in bowel habits, gut symptoms, and overall well-being through questionnaires and blood and stool samples. The goal is to see if probiotics can improve not just digestion, but also immune function and mental health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Probiotics (dietary supplement)
What this could lead to
If effective, this could offer a natural, over-the-counter option for managing constipation and improving overall gut health.
What could go wrong
The trial is small and early, and results may not apply to everyone. Probiotics can cause mild digestive upset in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 76 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 to 65 years (inclusive). * Diagnosed with constipation, defined as fewer than 3 spontaneous bowel movements per week and/or Bristol Stool Form Scale types 1 or 2. * Willing and able to comply with the study protocol and complete all required assessments. * Provide written informed consent prior to any study-related procedures. * Male and female participants of childbearing potential must agree to use effective contraception voluntarily from 14 days prior to screening until 6 months after the end of the trial. Female participants of non-childbearing potential (e.g., post-menopausal or surgically sterile) are exempt from this requirement. Exclusion Criteria: * Use of products with functions similar to the investigational product within a short period prior to screening that may interfere with the evaluation of study outcomes. * Intention to change dietary habits significantly during the study period. * Severe allergies or immunodeficiency. * Women who are pregnant, breastfeeding, or planning to become pregnant during the trial. * Severe diseases of vital organs (including cardiovascular, pulmonary, hepatic, or renal disease), metabolic diseases (e.g., diabetes, thyroid disorders), malignancy, or severe immune system disorders. * Use of antibiotics within the past 30 days. * Severe psychological or psychiatric disorders. * Poor compliance (e.g., failure to take the test product as instructed or failure to attend scheduled follow-up visits) that would preclude a valid assessment of efficacy. * Organic constipation (e.g., caused by structural or pathological conditions). * Irritable bowel syndrome with constipation (IBS-C). * History of surgical procedures within 30 days prior to screening that may have caused or contributed to constipation symptoms. * Intake of probiotic or prebiotic supplements within one month prior to the start of the study. * Any other condition that, in the investigator's opinion, would make the participant unsuitable for participation in the study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Suzhou Ninth People's Hospital

    RECRUITING

    Suzhou, Jiangsu, 215000, China

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