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Can probiotics ease constipation? new trial seeks answers
NCT ID NCT07462481
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a probiotic supplement can safely relieve constipation in adults. About 105 people with chronic constipation will receive either the probiotic or a placebo. Researchers will track changes in stool consistency using the Bristol Stool Scale to see if the probiotic helps produce softer, more regular bowel movements.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 105 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: (1) Age 18-65 years; (2) Constipated patients (less than 3 bowel movements per week and/or Bristol Scale type 1 and 2); (3) Able to complete the study according to the trial protocol; (4) Patients who have signed the informed consent form; (5) Study participants (including male study participants) have no plans to have children within 14 days prior to screening and within 6 months after the end of the trial and voluntarily use effective contraception. \- Exclusion Criteria: 1. Those who have taken a substance with a similar function to the test subject in a short period of time, affecting their judgment of the results; 2. Patients who changed their diet during the study; 3. Patients with severe allergies and immunodeficiency; 4. Pregnant, breastfeeding, or women planning to become pregnant; 5. Those with severe diseases of vital organs such as the cardiovascular system, lungs, liver, and kidneys, diabetes, thyroid disease, severe metabolic diseases, malignant tumors, or severe immune system diseases; 6. Those who have used antibiotics in the past two weeks; 7. Those with severe psychological or mental illnesses; 8. Those who did not consume the test sample as required or did not follow up on time, resulting in the inability to determine the efficacy; 9. Other study participants deemed unsuitable by the researchers. -
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Suzhou Ninth People's Hospital
RECRUITINGSuzhou, Jiangsu, 215000, China
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