CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This study is testing whether an experimental injection called JKN2401 can help people with moderate-to-severe COPD. Researchers want to see if it reduces the frequency of serious breathing flare-ups compared to a placebo. About 888 participants will receive either the actual inj…

This early-stage study investigates whether metformin, a medication typically used for diabetes, is safe and well-tolerated in older adults with COPD who do not have diabetes. Researchers will enroll 45 participants to see if metformin changes certain blood markers related to agi…

This study tests whether a 12-month training program led by physiotherapists can help people with COPD use their inhalers correctly. About 116 participants will be randomly assigned to receive either the special training sessions plus usual care, or just their usual care. The mai…

This study is testing whether adding a traditional Chinese herbal medicine called Guben Kechuan Granules to standard care helps people with COPD recover better after a serious flare-up that required hospital care. Researchers will enroll 126 patients who are about to be discharge…

This study aims to understand how a daily triple-inhaler medication works in the lungs of people with moderate-to-severe COPD. Researchers will use a special type of MRI scan to see if the medication improves air flow in the lungs and how this relates to breathing tests and quali…

This is a very early study to test the safety of a new cell therapy called REGEND007 for people with COPD. The therapy uses special stem cells from the airways that may help repair damaged lung tissue. Researchers will give the cells through an IV to 12 participants and closely m…

This study aims to develop a faster, simpler way to screen for pulmonary embolism, a serious condition where a blood clot blocks an artery in the lungs. Researchers will test if a 1-minute heart rhythm recording from a smartphone device, analyzed by artificial intelligence, can a…

This study is testing whether a new, handheld ultrasonic device can measure lung function as accurately as the larger, standard machines used in hospitals. About 100 adults with chronic lung conditions like COPD or asthma will perform breathing tests using both devices. The goal …

This small pilot study is testing whether a program where pharmacists help people with COPD (Chronic Obstructive Pulmonary Disease) manage their medications is practical and acceptable. The goal is to see if this approach can improve medication safety and reduce shortness of brea…

This study is testing if a specific, fast-paced presentation style called Pecha Kucha can help people with severe COPD who use a non-invasive breathing machine. Researchers want to see if this short, visual training can improve patients' confidence in managing their condition, re…

This study is testing if special 'active' sports shoes, designed to make walking easier, can help people with severe COPD. Researchers will have 75 participants walk in their usual shoes and in the special shoes to see if they can walk farther and feel less breathless. The goal i…

This study aims to find out if a simple breath test, which measures a gas called nitric oxide, can predict future flare-ups (exacerbations) in people with COPD who are starting a three-in-one inhaler. Researchers will observe 120 patients for up to a year to see if their initial …

This study aims to find out if giving extra oxygen during a walking test helps people with chronic lung conditions like COPD or interstitial lung disease. Researchers will have 114 hospitalized patients perform two 6-minute walking tests—one with their usual oxygen level and one …

This study is testing a wearable patch system designed to monitor lung function in adults with COPD from their own homes. For about 10 months, participants will wear the patch daily and also use a standard handheld breathing test device to see how well the patch's measurements co…