Hypnosis may ease breathing trouble in COPD patients
NCT ID NCT07637604
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether several sessions of medical hypnosis can improve quality of life for people with COPD who still have severe shortness of breath despite standard treatment. About 154 adults with advanced COPD will be randomly assigned to either five hypnosis sessions or four standard phone calls. The main goal is to see if hypnosis leads to better breathing-related quality of life after six weeks.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 154 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>18 years * COPD (any etiology), referred by a pulmonologist and managed according to GOLD 2024 guidelines except for pulmonary rehabilitation that is not required * Outpatient follow-up * Residing in Paris or the inner suburbs for centers located within the city limits, or within a 30-minute drive for centers located outside the city limits of Paris. * Dyspnea rated as mMRC 3 or 4 * Having signed an informed consent form Exclusion Criteria: * Vulnerable individuals (under legal guardianship or curatorship) or deprived of liberty * Pregnant or breastfeeding women * Absolute or relative contraindication to the 6 minutes walk test, spirometry or body plethysmography * Current COPD exacerbation or exacerbation resolved less than one week ago * Psychosis or other psychiatric disorder likely to interfere with study participation * Profound hearing impairment * Cognitive impairment * Use of psychedelic substances (ex: LSD (Lysergic acid diethylamide), psilocybin, etc.) * Current participation in interventions that may be related to hypnosis: any kind of meditation, relaxation, sophrology, heart coherence training, yoga, Qi Gong, holotropic breathing, EMDR (Eye Movement Desensitization and Reprocessing) or any psychotherapies involving eye movements, as well as shamanic practices and brief psychotherapies or cognitive-behavioral therapies * Previous management of dyspnea using hypnosis * Ongoing pulmonary rehabilitation (physiotherapy outside a structured rehabilitation program initiated before study inclusion is not an exclusion criterion) * Inability to be reached by phone or teleconsultation * Lack of health insurance (French social security) coverage * Participation in another clinical trial * End of life
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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APHP, Hôpital Pitié-Salpêtrière
Paris, France, 75013, France
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