CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

This study follows 152 adults with COPD who start taking a three-in-one inhaler (budesonide/glycopyrronium/formoterol). Researchers measure changes in symptoms, quality of life, and lung attacks over 6 months. The goal is to see how well the treatment works in everyday life, not …

This study tests a new dry powder inhaler called HSK39004 in 180 adults aged 40–80 with chronic obstructive pulmonary disease (COPD). Participants are randomly assigned to receive either the active inhaler or a placebo for 4 weeks. The main goal is to see if the drug improves lun…

This study tests an experimental drug called astegolimab in people with chronic obstructive pulmonary disease (COPD) who have frequent flare-ups. About 1,290 current or former smokers will receive either the drug or a placebo for one year. The goal is to see if the drug reduces t…

This study tests a drug called tozorakimab in people with COPD who have had flare-ups in the past. The goal is to see if it can reduce the number of severe breathing attacks over time. About 1,700 adults who finished earlier studies will take either the drug or a placebo for long…

This study looks at whether omega-3 fatty acids and vitamin D supplements can help people with COPD who are losing weight and muscle (a condition called pulmonary cachexia). About 45 adults with COPD and cachexia will take either omega-3 or vitamin D supplements. Researchers will…

This study tests an investigational drug called tozorakimab in adults with symptomatic COPD who have had at least two moderate or one severe flare-up in the past year and have high levels of eosinophils (a type of white blood cell). Participants receive either tozorakimab or a pl…

This study tests an investigational drug called tozorakimab in about 1,450 adults with symptomatic COPD who have had at least two moderate or one severe flare-up in the past year. Participants must already be on standard inhaled therapy. The main goal is to see if the drug can re…

This study is testing a new way to screen for chronic obstructive pulmonary disease (COPD) using artificial intelligence (AI) that listens to cough sounds recorded on a smartphone. The goal is to create a simple, low-cost tool that can help detect COPD earlier, especially in plac…

This study looks at whether an 8-week mindfulness program (MBSR) can improve anxiety, depression, stress, and quality of life in people with COPD. About 44 adults with COPD who are already in a pulmonary rehab program will take part. They will attend weekly group sessions, a sile…

This study tests whether using gentle electrical pulses on the leg muscles can help people with COPD feel more confident exercising, have less shortness of breath during activity, and feel less tired. About 40 adults with mild to severe COPD will receive the treatment for 8 weeks…

This study tests a new device called SonoHeal that helps people with cystic fibrosis, bronchiectasis, or COPD clear mucus from their lungs. About 15 participants will try the device and compare it to their usual therapy. The goal is to see if SonoHeal is easy to use and works as …

This study looks at how often people with COPD have bladder issues (like leaking urine) and how much they know about pelvic floor health. Researchers will ask 30 adults with COPD to fill out questionnaires about their bladder symptoms and quality of life. The goal is to better un…

This study compares the ability to imagine movements (motor imagery) between people with COPD and those without the disease. Researchers will use questionnaires and timed tests to measure how vividly participants can visualize and feel movements. The goal is to better understand …

This study looks at how the health of blood vessels and genetics may be linked to early signs of COPD and emphysema. Over 4,300 adults from a larger heart study took part. Researchers measured lung function and used CT scans to check for lung damage, aiming to understand the role…

This study tests whether a wearable skin sensor can detect different levels of pain in 37 adults with cancer or COPD who have persistent pain. Participants wear the device for up to a week and report their pain levels. The goal is to create an algorithm that alerts caregivers whe…

This study tests whether providing air cleaners and monitoring indoor air quality can help older adults with COPD avoid lung flare-ups during wildfire smoke events. Twenty Kaiser Permanente members aged 65+ who use oxygen will receive air cleaners and sensors. The goal is to see …

This study looks at over 1,500 people in Russia with moderate-to-severe COPD who have frequent lung attacks (exacerbations). Researchers will collect information on their health habits, other illnesses, and current treatments to better understand this group. The goal is to descri…