CARDIOPULMONARY BYPASS

This study is a pilot test to see if a future large trial is possible. It compares two ways of storing platelets, a blood component that helps with clotting, before giving them to adult heart surgery patients who are bleeding. The goal is to see if platelets stored cold work as w…

This study is testing whether giving intravenous (IV) fish oil to high-risk patients after major heart surgery can help them recover better. The main goal is to see if it reduces a common complication called atrial fibrillation, an irregular heartbeat that can delay recovery. Abo…

This study is testing new plastic tubes used to connect patients to a heart-lung bypass machine during certain heart surgeries. The goal is to see if these new tubes are as safe and work as well as the tubes doctors already use. The study will involve 80 adults having planned hea…

This study is testing if a specific adjustment to a breathing machine's pressure settings can help children in two situations: after heart surgery using a heart-lung bypass machine, and in children with severe breathing failure who might need advanced life support. Researchers wa…

This study aims to measure exactly how long a heart-protecting solution called Del Nido cardioplegia keeps the heart safe during open-heart surgery. Researchers will enroll 80 adults having elective valve or aortic surgery and take small, timed blood samples during and after thei…

This study is testing if a special heart scan measurement, taken before surgery, can predict which patients will have a hard time coming off the heart-lung machine during their operation. Researchers will follow 213 adults having planned heart surgery to see if this scan result i…

This study aims to understand how different fluids used to fill heart-lung machines affect patients' blood chemistry during heart surgery. Researchers will compare four different fluid mixtures in 80 patients undergoing bypass or valve replacement surgery. They will measure blood…