CARDIOPULMONARY BYPASS

This study tests new plastic tubes (cannulas) used to connect patients to a heart-lung machine during heart surgery. The goal is to see if they are safe and work as well as current tubes. About 80 adults having planned heart surgery will take part. The study has two phases: first…

This study compares two ways of using a heart-lung machine during open surgery for a thoracoabdominal aortic aneurysm (a bulge in the main artery in the chest and belly). About 236 adults from four hospitals in China will be randomly assigned to one of two bypass techniques. The …

This study tests whether cold-stored platelets work as well as standard room temperature-stored platelets to control bleeding in adults having heart surgery. About 150 participants will be randomly assigned to receive one type of platelet transfusion. The goal is to see if a larg…

This study tests whether giving fish oil before heart surgery can prevent a common complication called atrial fibrillation (irregular heartbeat) in high-risk patients. About 550 adults having elective heart surgery will receive either fish oil or a placebo (salt water) through an…

This study looks at why some infants develop lung injury after heart surgery that uses a heart-lung machine. Researchers will analyze blood and lung fluid samples from 56 babies under 1 year old to understand how immune cells called neutrophils contribute to this complication. Th…

This study looks at how different fluids used to fill the heart-lung machine affect the body's balance during heart surgery. About 80 adults having coronary bypass or aortic valve replacement will be split into four groups, each receiving a different priming solution. Researchers…

This study tests whether a personalized lung inflation technique can improve heart and lung function in two groups of children on breathing machines: those recovering from heart surgery and those with severe respiratory failure. Researchers will measure how well the lungs and hea…

This study watches 60 adults having heart surgery to see if lowering their body temperature changes the readings from two brain monitors (BIS and PSI). No new treatment is given—just careful observation. The goal is to help doctors give safer anesthesia during cooling procedures.…

This study looks at whether a special heart ultrasound measurement, called global longitudinal strain (GLS), can predict if a person will have a hard time coming off the heart-lung machine during heart surgery. Researchers will follow 213 adults having planned heart surgery and t…