CARDIOPULMONARY BYPASS

This study tested a special heart-protection plan given during heart surgery to see if it could reduce heart muscle damage compared to usual care. 210 adults having aortic valve surgery took part across multiple French hospitals. Researchers measured a heart damage marker in the …

This study tested whether dexmedetomidine, a sedative that preserves breathing better than other drugs, can protect the heart during cardiac bypass surgery. Researchers measured heart damage in 224 adults undergoing heart surgery with a heart-lung machine. The goal was to see if …

This study tested a new way to decide when to give blood transfusions during heart surgery. Instead of using a fixed hemoglobin level, doctors used a measure of oxygen in the blood (SvO2) to guide transfusions. The goal was to see if this approach could safely reduce the number o…

This study looked at 60 obese patients having heart surgery with a heart-lung machine. It compared two ways of giving the blood thinner heparin: one based on actual body weight and one based on ideal body weight. The goal was to see if using ideal body weight could prevent too mu…

This study tested whether giving a low dose of dexmedetomidine at night can prevent delirium (sudden confusion) in older adults after heart surgery. About 500 patients aged 60-89 were enrolled. The drug aims to improve sleep and reduce brain complications, potentially improving s…

This study tested whether using low tidal volume (gentle) ventilation during heart-lung bypass surgery could lower the risk of postoperative delirium (sudden confusion). 130 adults having planned heart surgery were randomly assigned to receive either gentle ventilation or no vent…

This study looked at 80 adults having heart valve or aortic surgery to find out how long Del Nido cardioplegia (a solution that stops the heart during bypass) keeps the heart safe. Researchers took blood samples at set times to see when heart damage starts to appear. The goal is …

This study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery that uses a heart-lung machine. Researchers measured this in 40 adults undergoing elective heart surgery…

This study looked at 40 adults having heart surgery with a heart-lung machine. The goal was to measure how fast pulse waves travel from the heart to different parts of the body. This helps doctors understand why blood pressure readings can differ between the arm and the leg durin…

This study looked at how two different oxygenators (artificial lungs used in heart-lung machines) affect platelet function during open-heart surgery. Platelets help blood clot, and damage to them can cause bleeding. Researchers tested 68 adults having non-emergency heart surgery …

This study compared two different solutions used to protect the heart during coronary artery bypass surgery. Forty adults having non-urgent bypass surgery at a Swedish hospital took part. Researchers measured heart damage markers in blood samples and checked recovery outcomes lik…

This study looked at 38 adults having heart surgery to better understand how the heart muscle gets injured during the procedure. Researchers used cardiac MRI scans and blood tests (troponin levels) to measure damage and swelling. The goal was to find links between the two methods…