CARDIOPULMONARY BYPASS
Clinical trials for CARDIOPULMONARY BYPASS explained in plain language.
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Heart surgery study aims to cut unnecessary blood transfusions
Disease control CompletedThis study tested whether doctors could safely give fewer blood transfusions during heart surgery by using a special monitor that checks how much oxygen the body's tissues are using. Researchers compared two groups of 676 adult heart surgery patients: one group received transfusi…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New heart surgery strategy aims to protect Patients' hearts
Disease control CompletedThis study tested whether a combination of protective treatments during heart valve surgery could reduce heart muscle damage compared to standard care. Researchers enrolled 210 patients undergoing aortic valve surgery and measured heart injury markers for 72 hours after surgery. …
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New dosing method aims to cut bleeding risk in obese heart surgery patients
Disease control CompletedThis study tested a new way to calculate the dose of the blood-thinner heparin for obese patients during heart surgery using a heart-lung machine. Researchers compared dosing based on a patient's ideal body weight versus their total weight to see if it prevented excessive blood t…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Sedative tested as heart protector in major surgery
Disease control CompletedThis study tested whether a sedative drug called dexmedetomidine could help protect the heart during and after major open-heart surgery. Researchers enrolled 224 patients undergoing this type of surgery to see if the drug reduced levels of a protein that signals heart muscle dama…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Gentle breathing during surgery may protect the mind
Symptom relief CompletedThis study tested whether using a gentle, low-volume breathing technique during heart surgery could reduce the risk of post-surgery delirium, a common and serious type of confusion. Researchers compared this technique to stopping breathing entirely during a specific part of the o…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Nevsehir Public Hospital • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Doctors test eye scan as window to the brain during risky heart operations
Knowledge-focused CompletedThis study tested if a simple, non-invasive eye ultrasound could detect dangerous pressure changes in the brain during open-heart surgery. Researchers measured the width of the optic nerve sheath in 40 adult patients at different points during their operation. The goal was to see…
Matched conditions: CARDIOPULMONARY BYPASS
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Apr 04, 2026 00:04 UTC
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Heart surgery study tests which protection method works better
Knowledge-focused CompletedThis study compared two different solutions used to protect the heart during coronary artery bypass surgery. Researchers enrolled 40 patients undergoing bypass surgery and monitored their recovery for 48 hours after the procedure. The goal was to understand which protection metho…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: PHASE4 • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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MRI scans reveal hidden heart damage after surgery
Knowledge-focused CompletedThis study aimed to better understand the heart muscle damage that can occur during open-heart surgery using a heart-lung machine. Researchers used detailed heart MRI scans and frequent blood tests to measure this damage in 38 patients who had aortic valve surgery. The goal was t…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Doctors probe hidden blood pressure gaps in heart surgery
Knowledge-focused CompletedThis study aimed to understand why blood pressure readings can differ between the body's core and limbs during heart-lung bypass surgery. Researchers measured pulse waves in 40 patients undergoing scheduled heart surgery to see if this difference could be reliably detected. The g…
Matched conditions: CARDIOPULMONARY BYPASS
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC