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Eye ultrasound may help monitor brain pressure during heart surgery

NCT ID NCT07253922

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery when patients are on a heart-lung machine. Researchers measured the optic nerve sheath diameter in 40 adults at several points during surgery. The goal was to see if this simple, non-invasive technique could help monitor brain pressure when direct measurement isn't possible.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a non-invasive way to monitor brain pressure during heart surgery, potentially improving patient safety.
What could go wrong
This is a small, completed observational study with only 40 participants. It does not test a treatment, and the method needs much larger studies to confirm it works reliably.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jun 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (18-85 years) undergoing elective open-heart surgery with cardiopulmonary bypass at Istanbul Medipol University Hospital, who meet inclusion criteria and provide written informed consent.

Ages

18 to 85 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-85 years * Scheduled for elective open-heart surgery with cardiopulmonary bypass * Provided written informed consent Exclusion Criteria: * Ocular or neurological complications related to diabetes * History of previous eye, brain, or thoracic surgery * Diagnosis of hydrocephalus, glaucoma, intracranial mass, or stroke

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medipol University

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.