Eye ultrasound may help monitor brain pressure during heart surgery
NCT ID NCT07253922
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery when patients are on a heart-lung machine. Researchers measured the optic nerve sheath diameter in 40 adults at several points during surgery. The goal was to see if this simple, non-invasive technique could help monitor brain pressure when direct measurement isn't possible.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a non-invasive way to monitor brain pressure during heart surgery, potentially improving patient safety.
- What could go wrong
- This is a small, completed observational study with only 40 participants. It does not test a treatment, and the method needs much larger studies to confirm it works reliably.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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40 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (18-85 years) undergoing elective open-heart surgery with cardiopulmonary bypass at Istanbul Medipol University Hospital, who meet inclusion criteria and provide written informed consent.
- Ages
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18 to 85 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-85 years * Scheduled for elective open-heart surgery with cardiopulmonary bypass * Provided written informed consent Exclusion Criteria: * Ocular or neurological complications related to diabetes * History of previous eye, brain, or thoracic surgery * Diagnosis of hydrocephalus, glaucoma, intracranial mass, or stroke
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medipol University
Istanbul, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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