CANCER

This study tested an experimental drug called PLX038 for people with advanced triple-negative breast cancer that had stopped responding to other treatments. Participants received the drug through an IV every three weeks to see if it could shrink their tumors. The trial was termin…

This study tested whether adding pembrolizumab (an immunotherapy drug) to standard chemotherapy could help people with lung cancer that had spread to their brain but wasn't causing symptoms. The goal was to see if this approach could control the cancer in the brain and body while…

This early-stage study tested whether combining a precise form of radiation (radiosurgery) with an immunotherapy drug (pembrolizumab) was safe and feasible for people with cancer that had spread to the spine. The main goal was to see if patients could complete both treatments. Re…

This study tested whether adding two drugs, venetoclax and azacitidine, as ongoing 'maintenance therapy' could help people with acute myeloid leukemia (AML) live longer after a stem cell transplant. It compared this drug combination to standard supportive care alone. The goal was…

This study tested a combination of two immunotherapy drugs, durvalumab and tremelimumab, for people with advanced rare solid tumors who had no other standard treatment options. The goal was to see if the drugs could shrink tumors and were safe for patients. The trial was designed…

This trial tested a personalized cancer vaccine made from each patient's own tumor tissue. The study aimed to see if this vaccine could delay cancer progression and improve survival in people with various solid tumors. Researchers also monitored safety and whether the vaccine tri…

This study tested a new cancer treatment called SQ3370 in patients with advanced solid tumors that had spread or could not be removed by surgery. The main goals were to find a safe dose and see if the treatment could shrink tumors. It involved 53 patients with specific types of c…

This study tested a personalized approach for children and young adults whose neuroblastoma (a nerve cell cancer) had returned or stopped responding to standard treatments. Doctors first performed a tumor biopsy to look for specific genetic changes. If a matching change was found…

This early-stage study tested a new drug called OC-001, both by itself and combined with an existing immunotherapy drug, in people with various advanced cancers that had stopped responding to standard treatments. The main goal was to check the safety of the drug and see how the b…

This study tested whether a special imaging technique called Narrow Band Imaging (NBI) could help surgeons see the edges of oral cancer tumors more clearly during surgery. It involved 23 adults with newly diagnosed, untreated oral cavity cancer who were scheduled for surgery. The…

This study tested a new, high-resolution PET/CT scanning technology to see if it could find small cancerous tumors more accurately than the standard scans used today. It involved 11 adult cancer patients who were already scheduled for a standard PET/CT scan. The goal was to see i…

This study tested if a 4-week stop-smoking program before major surgery could reduce complications after the operation. It involved 251 adult smokers scheduled for cancer or other major surgeries. The goal was to see if the structured quitting program led to fewer health problems…

This study aimed to see if digital health tools, like smartphone apps, could help cancer patients better manage their symptoms and improve their quality of life while receiving standard drug treatments. It involved 49 participants with specific types of lung or liver cancer. The …

This study tested a morphine gel applied directly to painful mouth sores caused by chemotherapy in children and young adults. The goal was to see if putting the pain medicine right on the sore spots worked better for pain relief than standard treatments. Researchers compared the …

This study tested two educational programs designed to help parents with late-stage, non-curable cancer communicate with their children aged 5-17. The goal was to improve the parent-child relationship, boost the parent's confidence in discussing the illness, and reduce anxiety an…

This study tested an online support group designed to help young adults who have finished cancer treatment cope with anxiety and depression during the COVID-19 pandemic. Researchers wanted to see if teaching healthy coping skills through virtual meetings could improve participant…

This study aimed to see if bringing specialized comfort care (palliative care) into patients' homes could improve their well-being and reduce hospital visits. It focused on adults with serious conditions like cancer, heart failure, or COPD who were not in hospice. The trial compa…

This study tested a new electronic platform designed to help doctors better understand the overall health of older adults with cancer. It involved patients aged 65+, their caregivers, and their oncology teams to see if the platform was easy to use and practical. The goal was to g…

This study created a registry to understand the health, wellbeing, and needs of young adults who survived cancer diagnosed between ages 18 and 39. Participants completed online surveys every 6 to 12 months to track their mental health, social support, and financial challenges. Th…

This study aimed to understand how COVID-19 affects people with cancer. Researchers screened patients receiving cancer treatment for silent (asymptomatic) COVID-19 infections and checked their blood for signs of an immune response. The goal was to gather crucial information to pr…

This was a laboratory study that tested two different sources of human cells to see which one could be better for making a non-stick medical patch. Researchers collected small tissue samples from six patients during surgery and grew the cells in a lab. The goal was to compare the…

This study aimed to collect fluid samples from the abdomen or chest and blood from adults with solid tumors. The goal was to analyze these samples to better understand cancer biology. Researchers hoped this knowledge would help develop improved cancer treatments in the future. No…

This study aimed to understand how exposure to chemicals from everyday products and pollution during pregnancy might affect future cancer risks for both mothers and their children. Researchers planned to follow over 1,500 pregnant women and their kids for several years, collectin…