CANCER

This trial tested a personalized cancer vaccine made from a patient's own tumor cells. It aimed to see if the vaccine could slow tumor growth or improve survival in people with various solid tumors. The study was stopped early, but researchers were looking at safety, immune respo…

This study tested a new drug called OC-001, either by itself or combined with avelumab (an immunotherapy), in people with advanced cancers that had spread. The goal was to check safety and how the drug moves through the body. The trial was stopped early, and only 73 people were e…

This study tested whether adding the drug pembrolizumab to chemotherapy could help people with non-small cell lung cancer that has spread to the brain but is not causing symptoms. The goal was to see if the combination could control the cancer in the brain and improve survival. H…

This study tested whether two drugs, venetoclax and azacitidine, could help people with acute myeloid leukemia (AML) live longer after a stem cell transplant. The trial included adults and teenagers who had a stem cell transplant or were planning one. The goal was to see if this …

This study looked at whether a structured smoking cessation program, started four weeks before surgery, could reduce complications in smokers undergoing intermediate to high-risk operations. The trial planned to enroll 251 patients but was terminated early. The goal was to compar…

This study tested a new drug called PLX038 in 14 people with advanced triple-negative breast cancer that had already been treated. The goal was to see if the drug could shrink tumors. The trial was stopped early, so results are limited.

This study tested a personalized approach for children with neuroblastoma that had come back or not responded to treatment. Doctors analyzed each child's tumor genes to pick a combination of targeted drugs. The goal was to control the cancer, not cure it, and the trial was stoppe…

This study tested a combination of two immunotherapy drugs (durvalumab and tremelimumab) in people with advanced rare solid tumors that had not responded to standard treatments. The goal was to see if the drugs could shrink tumors and to check for side effects. The trial was term…

This early-stage study tested whether combining precise radiation to the spine with the immunotherapy drug pembrolizumab is feasible for people with advanced spinal tumors pressing on the spinal cord. Only one person enrolled before the study was stopped early. The goal was to se…

This early-stage study tested a new drug called INKmune in people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The goal was to see if it was safe and to find the best dose. Only 2 people took part before the study was stopped early.

This study tested an experimental drug called SQ3370 in 53 people with advanced solid tumors that had stopped responding to other treatments. The main goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited.

This study tested a new imaging technique called AWSM-PET/CT, which aims to improve the detection of small cancerous spots that standard PET/CT scans might miss. Eleven adults with known or suspected cancer received both a standard scan and the enhanced AWSM scan. The goal was to…

This study tested whether a special light technique called Narrow Band Imaging (NBI) can help surgeons find early cancer spots in the mouth that are hard to see with the naked eye. The trial included 23 adults with untreated oral cancer who were scheduled for surgery. The goal wa…

This study tested an online support group for young adults (ages 18-39) who had cancer treatment and were feeling anxious or distressed during the pandemic. The goal was to see if teaching healthy coping skills through video sessions could improve their mood and confidence. The s…

This study tested a morphine gel applied directly to painful mouth sores caused by chemotherapy. The goal was to see if the gel could relieve pain better than standard intravenous morphine. The study included children and young adults aged 5 to 25 who had moderate to severe mouth…

This study tested two educational programs for parents with late-stage cancer who have children aged 5 to 17. The programs were designed to help parents talk with their children about cancer and improve family relationships. The goal was to reduce anxiety and depression in both p…

This study tested whether providing palliative care at home, through primary care clinics, helps seriously ill patients with cancer, heart failure, or COPD feel better. About 35 patients were enrolled, and researchers measured symptoms, anxiety, and depression. The goal was to im…

This study looked at how COVID-19 impacts people with cancer. Researchers measured how many cancer patients had COVID-19 without symptoms and how their immune systems responded. The study included 83 participants but was stopped early.

This study looked at how cancer patients experience being rotated at different speeds in the Nano-X patient rotation system. Researchers measured changes in anxiety and motion sickness using questionnaires before and after rotation. The study included 43 adults with any stage of …

This study looked at whether using digital health tools (like apps or online surveys) could help people receiving cancer treatment manage their symptoms and reduce visits to the doctor or hospital. About 49 adults with certain cancers were enrolled, but the study was stopped earl…

This research registry looks at the health, well-being, and needs of people who survived cancer as young adults (diagnosed between ages 18 and 39). It tracks levels of anxiety, depression, social support, and financial distress by having participants fill out online surveys every…

This study aimed to find the best cell source for creating a non-stick patch to prevent adhesions in cancer patients. Researchers compared cells from the peritoneum and from fat tissue to see which could form a protective mesothelial layer. Only 6 adults participated before the s…

This study collected fluid from the abdomen or lungs, plus blood, from 22 adults with solid tumors. The goal was to learn more about how cancer works, not to test a new treatment. Researchers hope this knowledge will lead to better therapies in the future.

This study looked at how chemicals in everyday products and the environment might affect cancer risk in pregnant women and their children. Researchers measured levels of pollutants like PFAS, phthalates, and pesticides in 1,576 participants. The goal was to understand if pregnanc…

This study tested an electronic platform called eGAP designed to help older cancer patients (65+), their caregivers, and doctors assess health needs. The goal was to see if the platform was easy to use and practical in a real-world setting. The study was stopped early and enrolle…

This study screened cancer patients for genetic markers that affect how they respond to drugs. The goal was to use this information to quickly match patients to the right clinical trials and drug doses, saving time. Only 8 adults participated before the study ended. It was design…