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Quit smoking before surgery to cut complications, study finds

NCT ID NCT05192837

Disease control Sponsor: Luzerner Kantonsspital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a structured smoking cessation program starting four weeks before surgery could reduce complications in smokers undergoing intermediate to high-risk operations. Researchers planned to enroll 251 adult smokers scheduled for surgeries like abdominal, thoracic, or cancer-related procedures. The program included counseling and support, compared to just giving advice. The goal was to see if quitting or reducing smoking before surgery leads to fewer post-surgery problems and shorter hospital stays.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

251 people

The number who actually took part.

Started

Sep 2022

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient listed for intermediate or high-risk surgery at the Kantonsspital of Lucerne * Patient undergoing surgery in one of the following departments: Abdominal surgery, thoracic surgery, cardiac surgery, urology, gynaecology, vascular surgery or head and neck surgery * Date of surgery \>2 weeks after date of listing for surgery or discussion by tumor board * Current smokers, defined as daily smoking of at least one cigarette, cigar or pipe * Age over 18 years * Able to give signed written informed consent Exclusion Criteria: * Plastic surgery * Consumption of illegal drugs * Alcohol dependency defined as preexisting alcohol related disorders (eg. alcoholic psychosis, Alcohol abuse, Alcohol polyneuropathy, degeneration of nervous system due to alcohol, Alcoholic myopathy, Alcoholic liver disease) * Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia

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Conditions

The condition(s) this trial relates to.

benign urinary system neoplasm cancer digestive system cancer female reproductive organ cancer head and neck cancer Head and Neck Neoplasms malignant urinary system neoplasm neoplasm Postoperative Complications Smoking Smoking Cessation Smoking Reduction thoracic cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal cancer Cancer Gynecologic cancer Head and neck cancer Perioperative complication Postoperative complications Smoking Smoking cessation Smoking reduction Surgery Surgery--complications Thoracic cancer Urologic cancer

Contacts and locations

Locations

  • LUKS

    Lucerne, Canton of Lucerne, 6000, Switzerland

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