THORACIC CANCER

This study looks at whether proton therapy can safely treat tumors that have returned after previous radiation. Unlike standard X-ray radiation, proton beams are more targeted and may spare healthy tissue. The trial will enroll 1,800 adults with various cancers to see if this app…

This study tests a new drug called TNG462, given with other cancer medicines, for people with pancreatic or lung cancer that has a specific genetic change (MTAP loss). The goal is to find safe doses and see if the combination shrinks tumors. About 183 adults with advanced cancer …

This study tests if a drug called Pedmark (sodium thiosulfate) can reduce hearing loss in adults receiving cisplatin chemotherapy for cancers like testicular, head and neck, or thoracic cancer. About 25 participants will receive Pedmark alongside their standard chemo. The goal is…

This study tests whether a virtual mind-body program called IM@Home can reduce fatigue and improve quality of life for adults with head and neck, thoracic, gynecologic, or other cancers who are receiving treatments like chemotherapy or radiation. About 480 participants will be en…

This study tests whether a specific nerve block (erector spinae block) can lower pain and the need for painkillers after lung surgery. About 70 adults having lung tumor removal will receive the block or standard care. Researchers will track pain scores and medication use for 24 h…

This study is collecting information from 500 people who need a second round of high-dose radiation for lung or other chest cancers. The goal is to learn how to give this treatment more safely by tracking side effects and survival. Researchers hope the findings will help doctors …

This study tests whether extra support—like a patient navigator, text message check-ins, and an educational video—can help Black, Latinx, and older adults (70+) with advanced cancer get the genomic testing needed to join precision cancer trials. About 210 participants with gastro…

This study is gathering health information from 12,000 adults with lung or other chest cancers. Researchers want to see how factors like genes, lifestyle, and treatments affect outcomes in everyday medical practice. No new treatments are tested—just data collected to help doctors…

This study will test a new robotic system, the Medtronic Hugo™, for surgery on chest cancers. About 50 adults will have their tumor removed using this robot. The goal is to see if the robot is safe and works well for these operations.

This study looks at whether a quick test of heart and breathing patterns before major chest surgery can help predict which patients will have complications afterward. Researchers will enroll 130 adults undergoing surgery for lung, esophageal, or stomach cancer. The goal is to see…

This study explores whether wearable devices like an Apple Watch and a home pulse oximeter can collect useful health data from 40 lung cancer patients during proton beam radiotherapy. Participants will wear the devices from the start of treatment until two weeks after it ends, an…

This study looks at why cancer patients feel very tired during chemotherapy and radiation. Researchers will collect blood and stool samples from 125 adults with different cancers before, during, and after treatment. They aim to find links between fatigue and changes in genes and …